| Literature DB >> 21916193 |
Tatsuya Miyazaki1, Makoto Sohda, Makoto Sakai, Naritaka Tanaka, Shigemasa Suzuki, Takehiko Yokobori, Takanori Inose, Masanobu Nakajima, Minoru Fukuchi, Hiroyuki Kato, Motoyasu Kusano, Hiroyuki Kuwano.
Abstract
Esophageal motility disorders are classified primary and secondary, and primary esophageal motility disorders are classified esophageal achalasia and other diseases by manometry. An esophageal emptying disorder associated with insufficient relaxation of the lower esophageal sphincter (LES) and elimination of peristaltic waves on the esophageal body is the major abnormality of achalasia. Esophagogram, endoscopy, and manometry are used for diagnosis. As pharmacological therapy, administration of a calcium channel blocker or nitrate is useful. The pharmacological therapy is not recommended as long-term basic therapy but as a temporary treatment. At 1st, the balloon dilation method is chosen in treatment of achalasia Surgical treatment is indicated in the following cases: (1) Patients uneffected by balloon dilation, (2) Flask type with grade II to III dilation, and sigmoid type, (3) the gradual progression to the pathophysiological stage, (4) young patients, (5) complicated with esophageal cancer. Laparoscopic Heller-Dor procedure is the most popular surgical procedure, recently. It is somewhat difficult to perform surgical treatment for this functional disease. We should select the most suitable individualized treatment with efficient comprehension of the pathophysiological situation.Entities:
Mesh:
Year: 2011 PMID: 21916193
Source DB: PubMed Journal: Kyobu Geka ISSN: 0021-5252