Literature DB >> 21915449

Oral propranolol as a new treatment for facial infantile hemangioma: case report.

Rosane da Cruz Ferreira1, Francisco Romeu Locatelli Wolff, Ricardo Mörschbächer.   

Abstract

Hemangiomas are the most common benign tumors of infancy. Despite their self-limited course, infantile capillary hemangiomas can impair vital or sensory functions as vision and cause cosmetic deformity. The usual treatments include oral/intralesional steroids, alpha interferon, cytotoxins, pulsed dye laser and cosmetic surgery resection. These treatments are not free of multiple complications and toxic side effects. This report describes the case of a 3-month-old female baby with progressively increasing hemangioma of the left upper eyelid impinging over the visual field. The hemangioma promptly responded to low-dose oral propranolol. A clinical response was noticed few days after the beginning of the treatment, with regression to 1/4 of its original size in 45 days of treatment, and to less than 1/10 after 8 months, free of any major side effects.

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Year:  2011        PMID: 21915449     DOI: 10.1590/s0004-27492011000300012

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  2 in total

1.  Efficacy of topical brimonidine-timolol for haemangioma of infancy and perils of off-label prescribing.

Authors:  Melinda B Chu; Garrett Searcy; Elaine Siegfried
Journal:  BMJ Case Rep       Date:  2013-04-17

Review 2.  Propranolol in use for treatment of complex infant hemangiomas: literature review regarding current guidelines for preassessment and standards of care before initiation of therapy.

Authors:  Andreas Fette
Journal:  ScientificWorldJournal       Date:  2013-05-20
  2 in total

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