Literature DB >> 21914119

Spinal cord stimulation utilization to treat the microcirculatory vascular insufficiency and ulcers associated with scleroderma: a case report and review of the literature.

David A Provenzano1, Luke Nicholson, Gaye Jarzabek, Evan Lutton, David B Catalane, Eileen Mackin.   

Abstract

OBJECTIVE: To report a case of scleroderma with associated Raynaud's phenomenon and its successful treatment with spinal cord stimulation. To demonstrate the use of transcutaneous oxygen pressure monitoring to guide the progression from trial to implantation and to assess post-implantation microcirculatory recovery.
DESIGN: Case report and literature review. PATIENT: A 51-year-old female with scleroderma, associated Raynaud's phenomenon, and a non-healing 3.7-cm lower extremity ischemic ulcer. Ankle-brachial indexes demonstrated normal macrocirculation, but transcutaneous oxygen pressures demonstrated significant microcirculatory insufficiency. INTERVENTION: Treatment was a spinal cord stimulator implantation after a successful trial. Transcutaneous oxygen pressures were interpreted during the trial and post-implantation stages. Results.  Based on a 5-day trial that documented improvements in transcutaneous oxygen pressures and pain relief, the patient underwent implantation. At 4 months, the ischemic ulcer had healed. The patient had significant improvement in pain control and reduced Raynaud's phenomenon signs and symptoms. At 18 months, the patient continued to have improvement with no associated complications. A literature review demonstrated only four published reports, including a total of 18 patients, on spinal cord stimulator treatment for scleroderma and associated Raynaud's phenomenon.
CONCLUSIONS: We report the healing of a greater than 3-cm ischemic ulcer in an individual with normal macrocirculation but severe microcirculatory insufficiency from scleroderma. Improvements in microcirculation correlated with wound healing. Spinal cord stimulation may be considered for select individuals with microcirculatory reserves that can be modulated with treatment. Wiley Periodicals, Inc.

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Year:  2011        PMID: 21914119     DOI: 10.1111/j.1526-4637.2011.01214.x

Source DB:  PubMed          Journal:  Pain Med        ISSN: 1526-2375            Impact factor:   3.750


  3 in total

Review 1.  Spinal cord stimulation for intractable chronic pain.

Authors:  Leonardo Kapural
Journal:  Curr Pain Headache Rep       Date:  2014-04

2.  Spinal cord stimulation for the treatment of pain and toe ulceration associated with systemic sclerosis: a case report.

Authors:  Hiroyuki Ito; Takafumi Tanei; Kyoko Sugawara; Yu Sando; Naohiro Hori
Journal:  Fukushima J Med Sci       Date:  2022-02-25

Review 3.  The Effects of Spinal Cord Stimulators on End Organ Perfusion: A Literature Review.

Authors:  Harneel S Saini; Mina Shnoda; Ishveen Saini; Matthew Sayre; Shahzaib Tariq
Journal:  Cureus       Date:  2020-03-12
  3 in total

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