| Literature DB >> 21913145 |
Abstract
Choroidal neovascularisation secondary to pathological myopia is the most common cause of severe visual impairment in myopic patients younger than 50 years old. The typical features of myopic CNV in contrast to age-related macular degeneration as well as the anatomic characteristics have an impact on the parameters of the baseline and follow-up examinations. As the usually small fibrovascular lesions show a rapid progression in the spontaneous course of the disease and lead to irreversible damage to the photoreceptors, prompt initiation of treatment is mandatory. The superior functional results of anti-VEGF drugs provide the reason for the first-line status of this treatment modality. Increasing safety data and consistent results of prospective pilot trials have proved photodynamic therapy to be inferior. There are signs that PRN-based treatment algorithms may allow for less frequent dosing than in other retinal diseases. © Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2011 PMID: 21913145 DOI: 10.1055/s-0031-1281583
Source DB: PubMed Journal: Klin Monbl Augenheilkd ISSN: 0023-2165 Impact factor: 0.700