| Literature DB >> 219131 |
S J Collins, F W Ruscetti, R E Gallagher, R C Gallo.
Abstract
The HL-60 human promyelocytic leukemia cell line can be induced to terminally differentiate to mature myeloid cells sharing a number of functional characteristics with normal granulocytes including response to chemoattractants, development of complement receptors, phagocytosis, superoxide production, and nitroblue tetrazolium dye reduction. Hence the Me2SO-induced HL-60 cells provide a unique in vitro model for studying various important aspects of human myeloid cell differentiation.Entities:
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Year: 1979 PMID: 219131 PMCID: PMC2184853 DOI: 10.1084/jem.149.4.969
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307