Literature DB >> 21912798

A potent antitumor Zn2+ tetraazamacrocycle complex targeting DNA: the fluorescent recognition, interaction and apoptosis studies.

Jing-Han Wen1, Cheng-Ying Li, Zhi-Rong Geng, Xiao-Yan Ma, Zhi-Lin Wang.   

Abstract

A Zn(2+) tetraazamacrocycle complex (2) bearing three naphthalene moieties has been prepared. Complex 2 recognizes, binds and causes damage to DNA, and shows considerable cytotoxicity against human cervical (HeLa), breast (MCF-7) and lung (NCI-H157) cancer cell lines with a different apoptotic pathway from that of cisplatin. This journal is © The Royal Society of Chemistry 2011

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21912798     DOI： 10.1039/c1cc14107d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  [Zn(phen)(O,N,O)(H2O)] and [Zn(phen)(O,N)(H2O)] with O,N,O is 2,6-dipicolinate and N,O is L-threoninate: synthesis, characterization, and biomedical properties.

Authors:  Lee-Fang Chin; Siew-Ming Kong; Hoi-Ling Seng; Yee-Lian Tiong; Kian-Eang Neo; Mohd Jamil Maah; Alan Soo-Beng Khoo; Munirah Ahmad; Tzi-Sum Andy Hor; Hong-Boon Lee; Swee-Lan San; Soi-Moi Chye; Chew-Hee Ng
Journal:  J Biol Inorg Chem       Date:  2012-07-24       Impact factor: 3.358

2.  Crystal Structure, Cytotoxicity and Interaction with DNA of Zinc (II) Complexes with o-Vanillin Schiff Base Ligands.

Authors:  Mei-Ju Niu; Zhen Li; Guo-Liang Chang; Xiang-Jin Kong; Min Hong; Qing-fu Zhang
Journal:  PLoS One       Date:  2015-06-26       Impact factor: 3.240

3.  Stabilisation of Exotic Tribromide (Br3-) Anions via Supramolecular Interaction with A Tosylated Macrocyclic Pyridinophane. A Serendipitous Case.

Authors:  Álvaro Martínez-Camarena; Matteo Savastano; Carla Bazzicalupi; Antonio Bianchi; Enrique García-España
Journal:  Molecules       Date:  2020-07-10       Impact factor: 4.411

4.  Investigations into the Structure/Antibacterial Activity Relationships of Cyclam and Cyclen Derivatives.

Authors:  Luis G Alves; João F Portel; Sílvia A Sousa; Olga Ferreira; Stephanie Almada; Elisabete R Silva; Ana M Martins; Jorge H Leitão
Journal:  Antibiotics (Basel)       Date:  2019-11-14

5.  Assembly of Polyiodide Networks with Cu(II) Complexes of Pyridinol-Based Tetraaza Macrocycles.

Authors:  Álvaro Martínez-Camarena; Matteo Savastano; Salvador Blasco; Estefanía Delgado-Pinar; Claudia Giorgi; Antonio Bianchi; Enrique García-España; Carla Bazzicalupi
Journal:  Inorg Chem       Date:  2021-12-21       Impact factor: 5.165
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.