Literature DB >> 21912462

Gut-liver axis plays a role in hepatocarcinogenesis of patients with Crohn's disease.

Shu-Mei Zheng, De-Jun Cui, Qin Ouyang.   

Abstract

The development of hepatocellular carcinoma (HCC) is attributed to several factors, including chronic viral infection, alcohol consumption, exposure to aflatoxin B1 and metabolic disorders. Several recent reports have shown that HCC can occur in patients with long-standing Crohn's disease (CD) in the absence of other underlying high-risk liver diseases. There may be an association between CD and hepatocarcinogenesis, however, the precise mechanism for this requires further investigations.

Entities:  

Keywords:  Azathioprine; Crohn’s disease; Enterohepatic circulation; Hepatocellular carcinoma; Inflammatory bowel disease; Intestinal flora

Mesh：

Substances：

Year:  2011        PMID： 21912462      PMCID： PMC3158419          DOI： 10.3748/wjg.v17.i26.3171

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  10 in total

1.  Meta-analysis of risk of malignancy with immunosuppressive drugs in inflammatory bowel disease.

Authors:  Yukari Masunaga; Keiko Ohno; Ryuichi Ogawa; Masayuki Hashiguchi; Hirotoshi Echizen; Hiroyasu Ogata
Journal:  Ann Pharmacother       Date:  2007-01-02       Impact factor: 3.154

2.  Hepatocellular carcinoma occurring in a Crohn's disease patient.

Authors:  Mitsuaki Ishida; Shigeyuki Naka; Hisanori Shiomi; Tomoyuki Tsujikawa; Akira Andoh; Tamio Nakahara; Yasuharu Saito; Yoshimasa Kurumi; Mikiko Takikita-Suzuki; Fumiyoshi Kojima; Machiko Hotta; Tohru Tani; Yoshihide Fujiyama; Hidetoshi Okabe
Journal:  World J Gastroenterol       Date:  2010-07-07       Impact factor: 5.742

Review 3.  The non-H pylori helicobacters: their expanding role in gastrointestinal and systemic diseases.

Authors:  J G Fox
Journal:  Gut       Date:  2002-02       Impact factor: 23.059

Review 4.  Emergence of diverse Helicobacter species in the pathogenesis of gastric and enterohepatic diseases.

Authors:  J V Solnick; D B Schauer
Journal:  Clin Microbiol Rev       Date:  2001-01       Impact factor: 26.132

Review 5.  The risk of cancer in patients with Crohn's disease.

Authors:  Alexander C von Roon; George Reese; Julian Teare; Vasilis Constantinides; Ara W Darzi; Paris P Tekkis
Journal:  Dis Colon Rectum       Date:  2007-06       Impact factor: 4.585

Review 6.  Are we giving azathioprine too late? The case for early immunomodulation in inflammatory bowel disease.

Authors:  María Josefina Etchevers; Montserrat Aceituno; Miquel Sans
Journal:  World J Gastroenterol       Date:  2008-09-28       Impact factor: 5.742

7.  Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine.

Authors:  A G Fraser; T R Orchard; E M Robinson; D P Jewell
Journal:  Aliment Pharmacol Ther       Date:  2002-07       Impact factor: 8.171

8.  Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.

Authors:  J G Fox; Y Feng; E J Theve; A R Raczynski; J L A Fiala; A L Doernte; M Williams; J L McFaline; J M Essigmann; D B Schauer; S R Tannenbaum; P C Dedon; S A Weinman; S M Lemon; R C Fry; A B Rogers
Journal:  Gut       Date:  2010-01       Impact factor: 23.059

9.  Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease.

Authors:  W R Connell; M A Kamm; M Dickson; A M Balkwill; J K Ritchie; J E Lennard-Jones
Journal:  Lancet       Date:  1994-05-21       Impact factor: 79.321

10.  DNA of Helicobacter spp. and common gut bacteria in primary liver carcinoma.

Authors:  W Abu Al-Soud; U Stenram; A Ljungh; K-G Tranberg; H-O Nilsson; T Wadström
Journal:  Dig Liver Dis       Date:  2007-12-20       Impact factor: 4.088
  10 in total
  2 in total

1.  Metastatic hepatocellular carcinoma in a patient with Crohn's disease treated with azathioprine and infliximab: a case report and literature review.

Authors:  Kyle J Fortinsky; Ali Alali; Khursheed Jeejeebhoy; Sandra Fischer; Morris Sherman; Scott Fung
Journal:  Case Rep Gastrointest Med       Date:  2014-12-22

2.  Recurrent Hepatocellular Carcinoma in Patient with Crohn's Disease: Incidental or Expected Outcome of Azathioprine?

Authors:  Youssef Botros; Mary Mathews; Hiren Patel; Nihar Shah; Walid Baddoura; Andrew de la Torre
Journal:  Case Rep Gastrointest Med       Date:  2015-12-14
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.