Ravi Kacker1, Stephen B Williams. 1. Department of Urology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 20015, USA.
Abstract
PURPOSE: To discern the positive and negative attributes of the various treatment modalities for benign prostatic hyperplasia. MATERIALS AND METHODS: A comprehensive literature review is presented for endoscopic treatment of the bladder outlet obstruction with an emphasis on current randomized controlled trials available comparing these treatment modalities. RESULTS: Transurethral resection of the prostate remains the gold standard when assessing alternative treatment options available for benign prostatic hyperplasia. Holmium laser enucleation of the prostate demonstrates equivalent efficacy with a more favorable risk profile. Photoselective vaporization, transurethral needle ablation, and transurethral microwave therapy have demonstrated safety and short-term efficacy; however, data on long-term efficacy are currently lacking. CONCLUSION: The current endoscopic methods may offer favorable safety and efficacy for the treatment of the bladder outlet obstruction. However, further research is needed to establish long-term efficacy for many of the currently available treatment options.
PURPOSE: To discern the positive and negative attributes of the various treatment modalities for benign prostatic hyperplasia. MATERIALS AND METHODS: A comprehensive literature review is presented for endoscopic treatment of the bladder outlet obstruction with an emphasis on current randomized controlled trials available comparing these treatment modalities. RESULTS: Transurethral resection of the prostate remains the gold standard when assessing alternative treatment options available for benign prostatic hyperplasia. Holmium laser enucleation of the prostate demonstrates equivalent efficacy with a more favorable risk profile. Photoselective vaporization, transurethral needle ablation, and transurethral microwave therapy have demonstrated safety and short-term efficacy; however, data on long-term efficacy are currently lacking. CONCLUSION: The current endoscopic methods may offer favorable safety and efficacy for the treatment of the bladder outlet obstruction. However, further research is needed to establish long-term efficacy for many of the currently available treatment options.
Authors: Rafael Marmiroli; Alberto A Antunes; Sabrina T Reis; Elcio Nakano; Miguel Srougi Journal: Clinics (Sao Paulo) Date: 2012-12 Impact factor: 2.365