Literature DB >> 21909525

DNA reorientation on Au nanoparticles: label-free detection of hybridization by surface enhanced Raman spectroscopy.

Evanthia Papadopoulou1, Steven E J Bell.   

Abstract

DNA sequences attached to Au nanoparticles via thiol linkers stand up from the surface, giving preferential enhancement of the adenine ring breathing SERS band. Non-specific binding via the nucleobases reorients the DNA, reducing this effect. This change in intensity on reorientation was utilised for label-free detection of hybridization of a molecular beacon.

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Year:  2011        PMID: 21909525     DOI: 10.1039/c1cc13705k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Bioanalytical applications of surface-enhanced Raman spectroscopy: de novo molecular identification.

Authors:  Anh H Nguyen; Emily A Peters; Zachary D Schultz
Journal:  Rev Anal Chem       Date:  2017-07-05       Impact factor: 3.067

Review 2.  Surface Enhanced Raman Spectroscopy for DNA Biosensors-How Far Are We?

Authors:  Edyta Pyrak; Jan Krajczewski; Artur Kowalik; Andrzej Kudelski; Aleksandra Jaworska
Journal:  Molecules       Date:  2019-12-04       Impact factor: 4.411

  2 in total

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