Literature DB >> 21909170

Microwave-Assisted Preparation of Trifluoroacetaldehyde (Fluoral): Isolation and Applications.

Shainaz M Landge1, Dmitry A Borkin, Béla Török.   

Abstract

A novel method for the preparation of trifluoroacetaldehyde (fluoral, TFAc, CF(3)CHO) from commercially available trifluoroacetaldehyde ethylhemiacetal (TFAE) by microwave irradiation is described. The isolation, characterization and reaction of fluoral with various nucleophiles were studied to verify the diverse applicability of this new method.

Entities:  

Year:  2007        PMID： 21909170      PMCID： PMC3170041          DOI： 10.1016/j.tetlet.2007.06.170

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  5 in total

1.  Fluorinated carbonyl and olefinic compounds: basic character and asymmetric catalytic reactions.

Authors:  Koichi Mikami; Yoshimitsu Itoh; Masahiro Yamanaka
Journal:  Chem Rev       Date:  2004-01       Impact factor: 60.622

2.  Highly enantioselective organocatalytic hydroxyalkylation of indoles with ethyl trifluoropyruvate.

Authors:  Béla Török; Mohammed Abid; Gábor London; Joseph Esquibel; Marianna Török; Shilpa C Mhadgut; Ping Yan; G K Surya Prakash
Journal:  Angew Chem Int Ed Engl       Date:  2005-05-13       Impact factor: 15.336

Review 3.  The chemistry of trifluoromethyl imines and related acetals derived from fluoral.

Authors:  Jean-Pierre Bégué; Danièle Bonnet-Delpon; Benoit Crousse; Julien Legros
Journal:  Chem Soc Rev       Date:  2005-04-08       Impact factor: 54.564

4.  SYNTHESIS OF TRIFLUOROMETHYL-IMINES BY SOLID ACID/SUPERACID CATALYZED MICROWAVE ASSISTED APPROACH.

Authors:  Mohammed Abid; Markku Savolainen; Shainaz Landge; Jinbo Hu; G K Surya Prakash; George A Olah; Béla Török
Journal:  J Fluor Chem       Date:  2007-06-01       Impact factor: 2.050

5.  Efficient asymmetric synthesis of alpha-trifluoromethyl-substituted primary amines via nucleophilic 1,2-addition to trifluoroacetaldehyde SAMP- or RAMP-hydrazone.

Authors:  D Enders; K Funabiki
Journal:  Org Lett       Date:  2001-05-17       Impact factor: 6.005
  5 in total
  1 in total

1.  Structure-activity relationships of organofluorine inhibitors of β-amyloid self-assembly.

Authors:  Béla Török; Abha Sood; Seema Bag; Aditya Kulkarni; Dmitry Borkin; Elizabeth Lawler; Sujaya Dasgupta; Shainaz Landge; Mohammed Abid; Weihong Zhou; Michelle Foster; Harry LeVine; Marianna Török
Journal:  ChemMedChem       Date:  2012-02-20       Impact factor: 3.466
  1 in total

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