Literature DB >> 2190900

Pyroglutamic acid improves the age associated memory impairment.

S Grioli1, C Lomeo, M C Quattropani, G Spignoli, C Villardita.   

Abstract

Pyroglutamic acid (PCA) was compared with placebo in a randomized, double blind trial for assessing its efficacy in treating memory deficits in 40 aged subjects. Twenty subjects were treated with PCA and 20 with placebo over a period of 60 d. Memory functions were evaluated at baseline and after 60 d of treatment by means of a battery made up of 6 memory tasks. The results suggest that PCA is effective in improving some verbal memory functions in subjects affected by age-related memory decline.

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Year:  1990        PMID: 2190900     DOI: 10.1111/j.1472-8206.1990.tb00485.x

Source DB:  PubMed          Journal:  Fundam Clin Pharmacol        ISSN: 0767-3981            Impact factor:   2.748


  4 in total

1.  The glutathione cycle shapes synaptic glutamate activity.

Authors:  Thomas W Sedlak; Bindu D Paul; Gregory M Parker; Lynda D Hester; Adele M Snowman; Yu Taniguchi; Atsushi Kamiya; Solomon H Snyder; Akira Sawa
Journal:  Proc Natl Acad Sci U S A       Date:  2019-01-28       Impact factor: 11.205

2.  Functional characterization of 5-oxoproline transport via SLC16A1/MCT1.

Authors:  Shotaro Sasaki; Yuya Futagi; Masaki Kobayashi; Jiro Ogura; Ken Iseki
Journal:  J Biol Chem       Date:  2014-11-04       Impact factor: 5.157

3.  Rice Bran Metabolome Contains Amino Acids, Vitamins & Cofactors, and Phytochemicals with Medicinal and Nutritional Properties.

Authors:  Iman Zarei; Dustin G Brown; Nora Jean Nealon; Elizabeth P Ryan
Journal:  Rice (N Y)       Date:  2017-06-02       Impact factor: 4.783

4.  Causal relationships between genetically determined metabolites and human intelligence: a Mendelian randomization study.

Authors:  Jian Yang; Binbin Zhao; Li Qian; Fengjie Gao; Yanjuan Fan; Xiaoyan He; Qingyan Ma; Lihong Yang; Bin Yan; Wei Wang; Xiancang Ma
Journal:  Mol Brain       Date:  2021-02-09       Impact factor: 4.041

  4 in total

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