Literature DB >> 21904730

Highly effective copper-catalyzed decarboxylative coupling of aryl halides with alkynyl carboxylic acids.

Xiaoming Qu1, Tingyi Li, Peng Sun, Yan Zhu, Hailong Yang, Jincheng Mao.   

Abstract

We have developed a highly effective copper-catalyzed decarboxylative coupling of alkynylcarboxylic acids with various aryl and alkyl halides at 2 mol% loading of copper. This method is simple, economical and practical for the synthesis of disubstituted alkyne compounds.

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Year:  2011        PMID： 21904730     DOI： 10.1039/c1ob05969f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  2 in total

1.  Practical synthesis of aryl-2-methyl-3-butyn-2-ols from aryl bromides via conventional and decarboxylative copper-free Sonogashira coupling reactions.

Authors:  Andrea Caporale; Stefano Tartaggia; Andrea Castellin; Ottorino De Lucchi
Journal:  Beilstein J Org Chem       Date:  2014-02-12       Impact factor: 2.883

2.  An Efficient and Sustainable Approach to Decarboxylative Cross-Coupling Using Silica Coated Magnetic Copper Nanocatalyst for the Synthesis of Internal Alkynes.

Authors:  Manavi Yadav; Anju Srivastava; Rashmi Gaur; Radhika Gupta; Gunjan Arora; Rakesh Kumar Sharma
Journal:  Front Chem       Date:  2022-01-17       Impact factor: 5.221
  2 in total

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