Literature DB >> 21904262

Carotid endarterectomy with primary closure: analysis of outcomes and review of the literature.

Georgios Zenonos1, Ning Lin, Albert Kim, Jeong Eun Kim, Lance Governale, Robert Max Friedlander.   

Abstract

BACKGROUND: Despite abundant published support of patch angioplasty during carotid endarterectomy (CEA), primary closure is still widely used. The reasons underlying the persistence of primary closure are not quite evident in the literature.
OBJECTIVE: To present our experience with primary closure in CEA, and provide a rationale for its persistent wide use.
METHODS: Medical records of all patients undergoing CEA by the senior author (R.F.) were retrospectively reviewed. Follow-up was supplemented with a telephone interview and completion of a structured questionnaire. A review of the current literature was performed.
RESULTS: From 1998 to 2010, the senior author performed 111 CEAs. Average cross-clamp time was 33 ± 11 minutes. Postoperative complications included 1 non-ST-elevation myocardial infarction and 2 strokes. No deaths, cranial-nerve deficits, or acute reocclusions were observed. After a mean follow-up of 64.6 months (7170.6 case-months), there were 3 contralateral strokes and 7 deaths. There were no ipsilateral strokes or restenoses >50%. Follow-up medication compliance was 94.6% for antiplatelet agents and 91.9% for statins. The outcomes of the current study were comparable to those of the available trials comparing patch angioplasty with primary closure. A careful evaluation of the literature revealed a number of reasons potentially explaining the persistent use of patch angioplasty.
CONCLUSION: In conjunction with contemporary medical management, primary closure during CEA may yield results comparable or superior to patch angioplasty. Advantages of primary closure include shorter cross-clamp times and elimination of graft-specific complications.

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Year:  2012        PMID: 21904262     DOI: 10.1227/NEU.0b013e3182351de0

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  4 in total

1.  Outcomes of Carotid Endarterectomy with Primary Closure.

Authors:  Ivy Cheng; Krishna S Vyas; Santhosh Velaga; Daniel L Davenport; Sibu P Saha
Journal:  Int J Angiol       Date:  2017-03-14

2.  Selective Patch Angioplasty and Intraoperative Shunting in Carotid Endarterectomy: A Single-Center Review of 141 Procedures.

Authors:  Rahul Kapoor; Alexander I Evins; Joshua Marcus; Luigi Rigante; Mayumi Kubota; Philip E Stieg
Journal:  Cureus       Date:  2015-10-28

3.  Comprehensive comparison of carotid endarterectomy primary closure and patch angioplasty: A single-institution experience.

Authors:  Nirmeen Zagzoog; Ali Elgheriani; Ahmed Attar; Radwan Takroni; Majid Aljoghaiman; Lisa Klotz; Cheyanne Vandervelde; Chloe Darling; Forrough Farrokhyar; Amanda Martyniuk; Almunder Algird
Journal:  Surg Neurol Int       Date:  2022-01-05

4.  Development and Validation of Ischemic Events Related Signature After Carotid Endarterectomy.

Authors:  Chunguang Guo; Zaoqu Liu; Can Cao; Youyang Zheng; Taoyuan Lu; Yin Yu; Libo Wang; Long Liu; Shirui Liu; Zhaohui Hua; Xinwei Han; Zhen Li
Journal:  Front Cell Dev Biol       Date:  2022-03-17
  4 in total

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