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Literature DB >> 21902816

Low frequency of Toll-like receptors 2 and 4 gene polymorphisms in Mexican patients and their association with type 2 diabetes.

C Maldonado-Bernal¹, A Trejo-de la O, M E Sánchez-Contreras, N Wacher-Rodarte, J Torres, M Cruz.

Abstract

Type 2 diabetes (T2D) is characterized by a chronic low-grade inflammatory state. SNP in Toll-like receptor (TLR) genes has been associated with impaired inflammatory response. We genotyped the TLR4/D299G, TLR4/T399I and TLR2/R753Q polymorphisms. Low frequency was found with no association with T2D, nevertheless the TLR2 SNP was associated with lower levels in HDL-cholesterol values.

Entities: Chemical Disease Gene Mutation Species

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Year: 2011 PMID： 21902816 DOI： 10.1111/j.1744-313X.2011.01035.x

Source DB: PubMed Journal: Int J Immunogenet ISSN： 1744-3121 Impact factor: 1.466

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Cited

8 in total

1. Toll-like receptor 4 D299G polymorphism in metabolic disorders: a meta-analysis.

Authors: F S Belforte; F Coluccio Leskow; E Poskus; A Penas Steinhardt
Journal: Mol Biol Rep Date: 2012-12-29 Impact factor: 2.316

2. Genetic Variants in Toll-Like Receptor 4 Gene and Their Association Analysis with Estimated Glomerular Filtration Rate in Mexican American Families.

Authors: Farook Thameem; Sobha Puppala; Vidya S Farook; Balakuntalam S Kasinath; John Blangero; Ravindranath Duggirala; Hanna E Abboud
Journal: Cardiorenal Med Date: 2016-05-20 Impact factor: 2.041

3. Impaired CD4+ and T-helper 17 cell memory response to Streptococcus pneumoniae is associated with elevated glucose and percent glycated hemoglobin A1c in Mexican Americans with type 2 diabetes mellitus.

Authors: Perla J Martinez; Christine Mathews; Jeffrey K Actor; Shen-An Hwang; Eric L Brown; Heather K De Santiago; Susan P Fisher Hoch; Joseph B McCormick; Shaper Mirza
Journal: Transl Res Date: 2013-08-05 Impact factor: 7.012

8. Association between Toll-Like Receptor 4 and Occurrence of Type 2 Diabetes Mellitus Susceptible to Pulmonary Tuberculosis in Northeast China.

Authors: Yuze Li; Dianzhong Li; Jinfeng Zhang; Shurui Liu; Haijun Chen; Kun Wu
Journal: Stem Cells Int Date: 2016-03-31 Impact factor: 5.443

8 in total

Low frequency of Toll-like receptors 2 and 4 gene polymorphisms in Mexican patients and their association with type 2 diabetes.

1. Toll-like receptor 4 D299G polymorphism in metabolic disorders: a meta-analysis.

2. Genetic Variants in Toll-Like Receptor 4 Gene and Their Association Analysis with Estimated Glomerular Filtration Rate in Mexican American Families.

3. Impaired CD4+ and T-helper 17 cell memory response to Streptococcus pneumoniae is associated with elevated glucose and percent glycated hemoglobin A1c in Mexican Americans with type 2 diabetes mellitus.

4. Association of toll-like receptor 4 polymorphisms with type 2 diabetes mellitus.

Review 5. Toll-like receptor 2 and type 2 diabetes.

Review 6. Genetic Epidemiology of Type 2 Diabetes in Mexican Mestizos.

7. Toll-Like Receptor 2 (TLR-2) Gene Polymorphisms in Type 2 Diabetes Mellitus.

8. Association between Toll-Like Receptor 4 and Occurrence of Type 2 Diabetes Mellitus Susceptible to Pulmonary Tuberculosis in Northeast China.