Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases.

Literature DB >> 21902672

Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases.

Abstract

Several sporadic neurodegenerative diseases display phenomena that directly or indirectly relate to mitochondrial function. Data suggesting altered mitochondrial function in these diseases could arise from mitochondrial DNA (mtDNA) are reviewed. Approaches for manipulating mitochondrial function and minimizing the downstream consequences of mitochondrial dysfunction are discussed.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：
DNA, Mitochondrial

Year: 2011 PMID： 21902672 PMCID： PMC3351798 DOI： 10.2174/138161211798072535

Source DB: PubMed Journal: Curr Pharm Des ISSN： 1381-6128 Impact factor: 3.116

309 in total

1. High frequency of mitochondrial complex I mutations in Parkinson's disease and aging.

Authors: Rafal Smigrodzki; Janice Parks; W Davis Parker
Journal: Neurobiol Aging Date: 2004 Nov-Dec Impact factor: 4.673

2. Rosiglitazone monotherapy in mild-to-moderate Alzheimer's disease: results from a randomized, double-blind, placebo-controlled phase III study.

Authors: Michael Gold; Claire Alderton; Marina Zvartau-Hind; Sally Egginton; Ann M Saunders; Michael Irizarry; Suzanne Craft; Gary Landreth; Ulla Linnamägi; Sharon Sawchak
Journal: Dement Geriatr Cogn Disord Date: 2010-08-21 Impact factor: 2.959

3. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.

Authors: Shinji Kume; Takashi Uzu; Kihachiro Horiike; Masami Chin-Kanasaki; Keiji Isshiki; Shin-Ichi Araki; Toshiro Sugimoto; Masakazu Haneda; Atsunori Kashiwagi; Daisuke Koya
Journal: J Clin Invest Date: 2010-03-24 Impact factor: 14.808

4. Nitric oxide is necessary for multiple memory processes after learning that a food is inedible in aplysia.

Authors: Ayelet Katzoff; Tziona Ben-Gedalya; Abraham J Susswein
Journal: J Neurosci Date: 2002-11-01 Impact factor: 6.167

Review 5. Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior.

Authors: Michael M Halassa; Philip G Haydon
Journal: Annu Rev Physiol Date: 2010 Impact factor: 19.318

6. 31P NMR study of improvement in oxidative phosphorylation by vitamins K3 and C in a patient with a defect in electron transport at complex III in skeletal muscle.

Authors: S Eleff; N G Kennaway; N R Buist; V M Darley-Usmar; R A Capaldi; W J Bank; B Chance
Journal: Proc Natl Acad Sci U S A Date: 1984-06 Impact factor: 11.205

7. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice.

Authors: Shan Zhu; Irina G Stavrovskaya; Martin Drozda; Betty Y S Kim; Victor Ona; Mingwei Li; Satinder Sarang; Allen S Liu; Dean M Hartley; Du Chu Wu; Steven Gullans; Robert J Ferrante; Serge Przedborski; Bruce S Kristal; Robert M Friedlander
Journal: Nature Date: 2002-05-02 Impact factor: 49.962

8. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

Authors: Paul H Gordon; Dan H Moore; Robert G Miller; Julaine M Florence; Joseph L Verheijde; Carolyn Doorish; Joan F Hilton; G Mark Spitalny; Robert B MacArthur; Hiroshi Mitsumoto; Hans E Neville; Kevin Boylan; Tahseen Mozaffar; Jerry M Belsh; John Ravits; Richard S Bedlack; Michael C Graves; Leo F McCluskey; Richard J Barohn; Rup Tandan
Journal: Lancet Neurol Date: 2007-11-05 Impact factor: 44.182

Review 9. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure.

Authors: Carles Cantó; Johan Auwerx
Journal: Curr Opin Lipidol Date: 2009-04 Impact factor: 4.776

10. Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease.

Authors: David K Simon; Michael T Lin; Leiya Zheng; Guang-Jun Liu; Colette H Ahn; Lauren M Kim; William M Mauck; Florence Twu; M Flint Beal; Donald R Johns
Journal: Neurobiol Aging Date: 2004-01 Impact factor: 4.673

20 in total

1. Dorsal Root Ganglia Mitochondrial Biochemical Changes in Non-diabetic and Streptozotocin-Induced Diabetic Mice Fed with a Standard or High-Fat Diet.

Authors: B L Guilford; J M Ryals; E Lezi; R H Swerdlow; D E Wright
Journal: J Neurol Neurosci Date: 2017-03-27

2. Beyond amyloid: getting real about nonamyloid targets in Alzheimer's disease.

Authors: Karl Herrup; Maria C Carrillo; Dale Schenk; Angela Cacace; Susan Desanti; Robert Fremeau; Ratan Bhat; Marcie Glicksman; Patrick May; Russell Swerdlow; Linda J Van Eldik; Lisa J Bain; Samantha Budd
Journal: Alzheimers Dement Date: 2013-07 Impact factor: 21.566

Review 3. Relationships Between Mitochondria and Neuroinflammation: Implications for Alzheimer's Disease.

Authors: Heather M Wilkins; Russell H Swerdlow
Journal: Curr Top Med Chem Date: 2016 Impact factor: 3.295

Review 4. The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.

Authors: Russell H Swerdlow; Jeffrey M Burns; Shaharyar M Khan
Journal: Biochim Biophys Acta Date: 2013-09-23

5. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis.

Authors: Heather M Wilkins; Janna L Harris; Steven M Carl; Lezi E; Jianghua Lu; J Eva Selfridge; Nairita Roy; Lewis Hutfles; Scott Koppel; Jill Morris; Jeffrey M Burns; Mary L Michaelis; Elias K Michaelis; William M Brooks; Russell H Swerdlow
Journal: Hum Mol Genet Date: 2014-07-15 Impact factor: 6.150