Literature DB >> 21902657

A review of oxidative stress related genes and new antioxidant therapy in diabetic nephropathy.

Jana Makuc1, Danijel Petrovič.   

Abstract

A genetic component of diabetes and its complications (including diabetic nephropathy (DN)) is obvious, but the causative genes and mechanisms have not yet been satisfactorily identified. Oxidative stress is a single mechanism relating all major pathways responsible for diabetic damage. Numerous oxidative stress-related genes are positional candidates (determined by GWAS) and candidate genes studies confirm the association of their polymorphisms with DN. We present here their overview and connection to the "new antioxidant" therapy principle.

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Year:  2011        PMID: 21902657     DOI: 10.2174/187152511798120949

Source DB:  PubMed          Journal:  Cardiovasc Hematol Agents Med Chem        ISSN: 1871-5257


  11 in total

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Journal:  World J Nephrol       Date:  2013-11-06

2.  Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus.

Authors:  Rabea Asleh; Farid M Nakhoul; Rachel Miller-Lotan; Hoda Awad; Dan Farbstein; Nina S Levy; Nakhoul Nakhoul; Theodore C Iancu; Irena Manov; Michael Laue; Maret G Traber; Katie M Lebold; Andrew P Levy
Journal:  Free Radic Biol Med       Date:  2012-06-27       Impact factor: 7.376

3.  GSTM1-null and GSTT1-active genotypes as risk determinants of primary open angle glaucoma among smokers.

Authors:  Miroslav Stamenkovic; Vesna Lukic; Sonja Suvakov; Tatjana Simic; Ivan Sencanic; Marija Pljesa-Ercegovac; Vesna Jaksic; Sinisa Babovic; Marija Matic; Aleksandra Radosavljevic; Ana Savic-Radojevic; Tatjana Djukic
Journal:  Int J Ophthalmol       Date:  2018-09-18       Impact factor: 1.779

4.  Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients.

Authors:  Inbal Dahan; Evgeny Farber; Nadia Thauho; Nakhoul Nakhoul; Adi Francis; Mohamad Awawde; Andrew P Levy; Daniel B Kim-Shapiro; Swati Basu; Farid Nakhoul
Journal:  J Diabetes Res       Date:  2015-06-11       Impact factor: 4.011

5.  Matrix Metalloproteinase 9 Gene Promoter (rs 3918242) Mutation Reduces the Risk of Diabetic Microvascular Complications.

Authors:  Zhongwen Zhang; Xiaoyun Wu; Tian Cai; Weiyi Gao; Xiaojun Zhou; Junyu Zhao; Jinming Yao; Hongxia Shang; Jianjun Dong; Lin Liao
Journal:  Int J Environ Res Public Health       Date:  2015-07-14       Impact factor: 3.390

6.  Association of A1538G and C2437T single nucleotide polymorphisms in heat shock protein-70 genes with diabetic nephropathy among South Indian population.

Authors:  Umapathy Dhamodharan; Krishnamoorthy Ezhilarasi; Balashanmugam Ponjayanthi; Dornadula Sireesh; Kunka Mohanram Ramkumar; Vijay Viswanathan
Journal:  Biosci Rep       Date:  2017-03-27       Impact factor: 3.840

7.  Association of NFKB1 gene polymorphism (rs28362491) with levels of inflammatory biomarkers and susceptibility to diabetic nephropathy in Asian Indians.

Authors:  Amar Gautam; Stuti Gupta; Mohit Mehndiratta; Mohini Sharma; Kalpana Singh; Om P Kalra; Sunil Agarwal; Jasvinder K Gambhir
Journal:  World J Diabetes       Date:  2017-02-15

8.  Association of the NAD(P)H oxidase p22 phox gene C242T polymorphism with type 2 diabetes mellitus, diabetic nephropathy, and carotid atherosclerosis with type 2 diabetes mellitus: A meta-analysis.

Authors:  Tao Li; Hai-Feng Xi; Hong-Min Luo; Wen-Xuan Liu; Xia Gao; Dian-Wu Liu; Lei Yang
Journal:  Meta Gene       Date:  2015-08-25

9.  Haptoglobin genotype and the rate of renal function decline in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study.

Authors:  Trevor J Orchard; Wanjie Sun; Patricia A Cleary; Saul M Genuth; John M Lachin; Paula McGee; Andrew D Paterson; Philip Raskin; Yefim Anbinder; Andrew P Levy
Journal:  Diabetes       Date:  2013-06-12       Impact factor: 9.461

10.  The Iron-Klotho-VDR Axis Is a Major Determinant of Proximal Convoluted Tubule Injury in Haptoglobin 2-2 Genotype Diabetic Nephropathy Patients and Mice.

Authors:  Inbal Dahan; Nadia Thawho; Evgeny Farber; Nakhoul Nakhoul; Rabea Asleh; Andrew P Levy; Yan Chun Li; Ofer Ben-Izhak; Farid Nakhoul
Journal:  J Diabetes Res       Date:  2018-09-03       Impact factor: 4.011

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