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Literature DB >> 21902583

C868T single nucleotide polymorphism and HIV type 1 disease progression among postpartum women in Kenya.

Robert Y Choi¹, Keith R Fowke, Jennifer Juno, Barbara Lohman-Payne, Julius O Oyugi, Elizabeth R Brown, Rose Bosire, Grace John-Stewart, Carey Farquhar.

Abstract

The C868T single nucleotide polymorphism in the CD4 receptor encodes an amino acid substitution of tryptophan for arginine in the third domain. Previous studies suggest that C868T increases the risk of HIV-1 acquisition; however, the influence of this single nucleotide polymorphism (SNP) on disease progression has not been established. The presence of the C868T polymorphism was not statistically significantly associated with HIV-1 disease progression outcomes in a cohort of postpartum Kenyan women.

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2011 PMID： 21902583 PMCID： PMC3358105 DOI： 10.1089/AID.2011.0095

Source DB: PubMed Journal: AIDS Res Hum Retroviruses ISSN： 0889-2229 Impact factor: 2.205

18 in total

1. The effects of the 32-bp CCR-5 deletion on HIV transmission and HIV disease progression in individuals with haemophilia.

Authors: K J Pasi; C A Sabin; P V Jenkins; H L Devereux; C Ononye; C A Lee
Journal: Br J Haematol Date: 2000-10 Impact factor: 6.998

2. A single amino acid substitution in a common African allele of the CD4 molecule ablates binding of the monoclonal antibody, OKT4.

Authors: S Lederman; J A DeMartino; B L Daugherty; I Foeldvari; M J Yellin; A M Cleary; N Berkowitz; I Lowy; N S Braunstein; G E Mark
Journal: Mol Immunol Date: 1991-11 Impact factor: 4.407

3. Validation of performance of the gen-probe human immunodeficiency virus type 1 viral load assay with genital swabs and breast milk samples.

Authors: Dana DeVange Panteleeff; Sandra Emery; Barbra A Richardson; Christine Rousseau; Sarah Benki; Sharon Bodrug; Joan K Kreiss; Julie Overbaugh
Journal: J Clin Microbiol Date: 2002-11 Impact factor: 5.948

4. Evolution and transmission of stable CTL escape mutations in HIV infection.

Authors: P J Goulder; C Brander; Y Tang; C Tremblay; R A Colbert; M M Addo; E S Rosenberg; T Nguyen; R Allen; A Trocha; M Altfeld; S He; M Bunce; R Funkhouser; S I Pelton; S K Burchett; K McIntosh; B T Korber; B D Walker
Journal: Nature Date: 2001-07-19 Impact factor: 49.962

5. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

Authors: Y Huang; W A Paxton; S M Wolinsky; A U Neumann; L Zhang; T He; S Kang; D Ceradini; Z Jin; K Yazdanbakhsh; K Kunstman; D Erickson; E Dragon; N R Landau; J Phair; D D Ho; R A Koup
Journal: Nat Med Date: 1996-11 Impact factor: 53.440

6. Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

Authors: Geraldine M A Gillespie; Rupert Kaul; Tao Dong; Hong-Bing Yang; Tim Rostron; Job J Bwayo; Peter Kiama; Tim Peto; Francis A Plummer; Andrew J McMichael; Sarah L Rowland-Jones
Journal: AIDS Date: 2002-05-03 Impact factor: 4.177

7. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.

Authors: M Samson; F Libert; B J Doranz; J Rucker; C Liesnard; C M Farber; S Saragosti; C Lapoumeroulie; J Cognaux; C Forceille; G Muyldermans; C Verhofstede; G Burtonboy; M Georges; T Imai; S Rana; Y Yi; R J Smyth; R G Collman; R W Doms; G Vassart; M Parmentier
Journal: Nature Date: 1996-08-22 Impact factor: 49.962

8. HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.

Authors: S A Migueles; M S Sabbaghian; W L Shupert; M P Bettinotti; F M Marincola; L Martino; C W Hallahan; S M Selig; D Schwartz; J Sullivan; M Connors
Journal: Proc Natl Acad Sci U S A Date: 2000-03-14 Impact factor: 11.205

C868T single nucleotide polymorphism and HIV type 1 disease progression among postpartum women in Kenya.

1. The effects of the 32-bp CCR-5 deletion on HIV transmission and HIV disease progression in individuals with haemophilia.

2. A single amino acid substitution in a common African allele of the CD4 molecule ablates binding of the monoclonal antibody, OKT4.

3. Validation of performance of the gen-probe human immunodeficiency virus type 1 viral load assay with genital swabs and breast milk samples.

4. Evolution and transmission of stable CTL escape mutations in HIV infection.

5. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

6. Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.

7. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.

8. HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.

9. Infant CD4 C868T polymorphism is associated with increased human immunodeficiency virus (HIV-1) acquisition.

10. Association of HLA types A1-B8-DR3 and B27 with rapid and slow progression of HIV disease.

Review 1. HIV Diagnosis and Treatment through Advanced Technologies.

2. The CD4 C868T Polymorphism and Its Correlation with HIV-1 Infection in a Chinese Population.