Literature DB >> 21902447

Mental illness and warfarin use in atrial fibrillation.

Graham A Walker1, Paul A Heidenreich, Ciaran S Phibbs, Alan S Go, Victor Y Chiu, Susan K Schmitt, Lakshmi Ananth, Susan M Frayne.   

Abstract

OBJECTIVES: To determine whether atrial fibrillation (AF) patients with mental health conditions (MHCs) were less likely than AF patients without MHCs to be prescribed warfarin and, if receiving warfarin, to maintain an International Normalized Ratio (INR) within the therapeutic range. STUDY
DESIGN: Detailed chart review of AF patients using a Veterans Health Administration (VHA) facility in 2003.
METHODS: For a random sample of 296 AF patients, records identified clinician-diagnosed MHCs (independent variable) and AF-related care in 2003 (dependent variables), receipt of warfarin, INR values below/above key thresholds, and time spent within the therapeutic range (2.0-3.0) or highly out of range. Differences between the MHC and comparison groups were examined using X2 tests and logistic regression controlling for age and comorbidity.
RESULTS: Among warfarin-eligible AF patients (n = 246), 48.5% of those with MHCs versus 28.9% of those without MHCs were not treated with warfarin (P = .004). Among those receiving warfarin and monitored in VHA, highly supratherapeutic INRs were more common in the MHC group; for example, 27.3% versus 1.6% had any INR >5.0 (P <.001). Differences persisted after adjusting for age and comorbidity.
CONCLUSIONS: MHC patients with AF were less likely than those without MHC to have adequate management of their AF care. Interventions directed at AF patients with MHC may help to optimize their outcomes.

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Year:  2011        PMID: 21902447

Source DB:  PubMed          Journal:  Am J Manag Care        ISSN: 1088-0224            Impact factor:   2.229


  11 in total

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2.  Outcomes of anticoagulation therapy in patients with mental health conditions.

Authors:  Helen T Paradise; Dan R Berlowitz; Al Ozonoff; Donald R Miller; Elaine M Hylek; Arlene S Ash; Guneet K Jasuja; Shibei Zhao; Joel I Reisman; Adam J Rose
Journal:  J Gen Intern Med       Date:  2014-02-19       Impact factor: 5.128

3.  Association Between Bipolar Disorder or Schizophrenia and Oral Anticoagulation Use in Danish Adults With Incident or Prevalent Atrial Fibrillation.

Authors:  Morten Fenger-Grøn; Claus Høstrup Vestergaard; Anette Riisgaard Ribe; Søren Paaske Johnsen; Lars Frost; Annelli Sandbæk; Dimitry S Davydow
Journal:  JAMA Netw Open       Date:  2021-05-03

4.  The effect of mental health conditions on the use of oral anticoagulation therapy in patients with atrial fibrillation: the FinACAF study.

Authors:  Jussi Jaakkola; Konsta Teppo; Fausto Biancari; Olli Halminen; Jukka Putaala; Pirjo Mustonen; Jari Haukka; Miika Linna; Janne Kinnunen; Paula Tiili; Aapo L Aro; Juha Hartikainen; K E Juhani Airaksinen; Mika Lehto
Journal:  Eur Heart J Qual Care Clin Outcomes       Date:  2022-05-05

Review 5.  Measures of vitamin K antagonist control reported in atrial fibrillation and venous thromboembolism studies: a systematic review.

Authors:  Elizabeth S Mearns; Jessica Hawthorne; Ju-Sung Song; Craig I Coleman
Journal:  BMJ Open       Date:  2014-06-20       Impact factor: 2.692

6.  Quality of vitamin K antagonist control and outcomes in atrial fibrillation patients: a meta-analysis and meta-regression.

Authors:  Elizabeth S Mearns; C Michael White; Christine G Kohn; Jessica Hawthorne; Ju-Sung Song; Joy Meng; Jeff R Schein; Monika K Raut; Craig I Coleman
Journal:  Thromb J       Date:  2014-06-24

7.  Impact of social determinants of health on anticoagulant use among patients with atrial fibrillation: Systemic review and meta-analysis.

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Journal:  Medicine (Baltimore)       Date:  2022-09-02       Impact factor: 1.817

8.  The unmeasured burden: Contribution of depression and psychological stress to patient-reported outcomes in atrial fibrillation.

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Review 9.  Atrial fibrillation and thromboprophylaxis in heart failure: the need for patient-centered approaches to address adherence.

Authors:  Caleb Ferguson; Sally C Inglis; Phillip J Newton; Sandy Middleton; Peter S Macdonald; Patricia M Davidson
Journal:  Vasc Health Risk Manag       Date:  2013-01-16

10.  Atrial fibrillation in patients with severe mental disorders and the risk of stroke, fatal thromboembolic events and bleeding: a nationwide cohort study.

Authors:  Mette Søgaard; Flemming Skjøth; Jette Nordstrøm Kjældgaard; Torben Bjerregaard Larsen; Søren Pihlkjær Hjortshøj; Sam Riahi
Journal:  BMJ Open       Date:  2017-12-06       Impact factor: 2.692

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