| Literature DB >> 21902200 |
Kazuya Okamoto1, Masahiro Sakagami, Fei Feng, Hiroko Togame, Hiroshi Takemoto, Satoshi Ichikawa, Akira Matsuda.
Abstract
The first total synthesis of pacidamycin D, which is expected to be a good candidate as an antibacterial agent against P. aeruginosa, is described. The key elements of our approach feature an efficient and stereocontrolled construction of the Z-oxyvinyl iodide and copper-catalyzed cross-coupling with the tetrapeptide carboxamide.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21902200 DOI： 10.1021/ol202124b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005