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Literature DB >> 21901398

MicroRNA-146a and hemopoietic disorders.

Zhong Hua¹, Wang Chun², Chen Fang-Yuan¹.

Abstract

MicroRNAs (MiRNAs) are a class of small non-coding regulatory RNAs that repress protein expression at the posttranscriptional level and play important roles in hematopoiesis processes. MiR-146a is a miRNA that is thought to regulate physiological and pathophysiological pathways in hematopoietic cells. In this review, we focus on recent progress in analyzing the functional roles of miR-146a in normal hematopoiesis and hematopoietic disease. We suggest that manipulation of miR-146a expression may represent a potential new therapy for several hematopoietic diseases, and may further serve as a biomarker for diagnosis, prevention, and treatment of such disease.

Entities: Disease Gene

Mesh：

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Year: 2011 PMID： 21901398 DOI： 10.1007/s12185-011-0923-7

Source DB: PubMed Journal: Int J Hematol ISSN： 0925-5710 Impact factor: 2.490

57 in total

Review 1. MicroRNAs in benign and malignant hematopoiesis.

Authors: Sharathkumar Bhagavathi; Magdalena Czader
Journal: Arch Pathol Lab Med Date: 2010-09 Impact factor: 5.534

2. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Authors: Hui-Kuan Lin; Zhenbang Chen; Guocan Wang; Caterina Nardella; Szu-Wei Lee; Chia-Hsin Chan; Chan-Hsin Chan; Wei-Lei Yang; Jing Wang; Ainara Egia; Keiichi I Nakayama; Carlos Cordon-Cardo; Julie Teruya-Feldstein; Pier Paolo Pandolfi
Journal: Nature Date: 2010-03-18 Impact factor: 49.962

3. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses.

Authors: Konstantin D Taganov; Mark P Boldin; Kuang-Jung Chang; David Baltimore
Journal: Proc Natl Acad Sci U S A Date: 2006-08-02 Impact factor: 11.205

4. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.

Authors: George Adrian Calin; Cinzia Sevignani; Calin Dan Dumitru; Terry Hyslop; Evan Noch; Sai Yendamuri; Masayoshi Shimizu; Sashi Rattan; Florencia Bullrich; Massimo Negrini; Carlo M Croce
Journal: Proc Natl Acad Sci U S A Date: 2004-02-18 Impact factor: 11.205

5. Karyotype-specific microRNA signature in chronic lymphocytic leukemia.

Authors: Rosa Visone; Laura Z Rassenti; Angelo Veronese; Cristian Taccioli; Stefan Costinean; Baltazar D Aguda; Stefano Volinia; Manuela Ferracin; Jeff Palatini; Veronica Balatti; Hansjuerg Alder; Massimo Negrini; Thomas J Kipps; Carlo M Croce
Journal: Blood Date: 2009-08-28 Impact factor: 22.113

Review 6. MicroRNA expression profiling in acute myeloid and chronic lymphocytic leukaemias.

Authors: Guido Marcucci; Krzysztof Mrózek; Michael D Radmacher; Clara D Bloomfield; Carlo M Croce
Journal: Best Pract Res Clin Haematol Date: 2009-06 Impact factor: 3.020

7. Interferon modulation of cellular microRNAs as an antiviral mechanism.

Authors: Irene M Pedersen; Guofeng Cheng; Stefan Wieland; Stefano Volinia; Carlo M Croce; Francis V Chisari; Michael David
Journal: Nature Date: 2007-10-18 Impact factor: 49.962

8. MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.

Authors: Ramiro Garzon; Stefano Volinia; Chang-Gong Liu; Cecilia Fernandez-Cymering; Tiziana Palumbo; Flavia Pichiorri; Muller Fabbri; Kevin Coombes; Hansjuerg Alder; Tatsuya Nakamura; Neal Flomenberg; Guido Marcucci; George A Calin; Steven M Kornblau; Hagop Kantarjian; Clara D Bloomfield; Michael Andreeff; Carlo M Croce
Journal: Blood Date: 2008-01-10 Impact factor: 22.113

Review 9. Adding fuel to fire: microRNAs as a new class of mediators of inflammation.

Authors: F J Sheedy; L A J O'Neill
Journal: Ann Rheum Dis Date: 2008-12 Impact factor: 19.103

10. Distinctive patterns of microRNA expression associated with karyotype in acute myeloid leukaemia.

Authors: Amanda Dixon-McIver; Phil East; Charles A Mein; Jean-Baptiste Cazier; Gael Molloy; Tracy Chaplin; T Andrew Lister; Bryan D Young; Silvana Debernardi
Journal: PLoS One Date: 2008-05-14 Impact factor: 3.240

9 in total

1. Involvement of TLR2-MyD88 in abnormal expression of miR-146a in peripheral blood monocytes of patients with chronic hepatitis C.

Authors: Wen-Jing Zhang; Hua Wang; Qiao-Xia Tong; Sheng-Hua Jie; Dong-Liang Yang; Cheng Peng
Journal: J Huazhong Univ Sci Technolog Med Sci Date: 2015-04-16

Review 2. Molecular basis of chronic lymphocytic leukemia diagnosis and prognosis.

Authors: Mohammad Shahjahani; Javad Mohammadiasl; Fatemeh Noroozi; Mohammad Seghatoleslami; Saeid Shahrabi; Fakhredin Saba; Najmaldin Saki
Journal: Cell Oncol (Dordr) Date: 2015-01-07 Impact factor: 6.730

3. A functional polymorphism in the miR-146a gene is associated with the risk of childhood acute lymphoblastic leukemia: a preliminary report.

Authors: Seyed-Shahaboddin Hasani; Mohammad Hashemi; Ebrahim Eskandari-Nasab; Majid Naderi; Mohsen Omrani; Maryam Sheybani-Nasab
Journal: Tumour Biol Date: 2013-07-27

4. Integrated analysis of miRNA and mRNA during differentiation of human CD34+ cells delineates the regulatory roles of microRNA in hematopoiesis.

Authors: Nalini Raghavachari; Poching Liu; Jennifer J Barb; Yanqin Yang; Richard Wang; Quang Tri Nguyen; Peter J Munson
Journal: Exp Hematol Date: 2013-10-16 Impact factor: 3.084

5. MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.

Authors: Shaolei Lu; Vincent A Mukkada; Shamlal Mangray; Kelly Cleveland; Nick Shillingford; Christoph Schorl; Alexander S Brodsky; Murray B Resnick
Journal: PLoS One Date: 2012-07-16 Impact factor: 3.240