| Literature DB >> 21898133 |
De-Wu Zhang1, Yan Yang, Fang Yao, Qun-Ying Yu, Sheng-Jun Dai.
Abstract
A new coumestan (solalyratin A, 1) and a novel cyclic eight-membered α,β-unsaturated ketone (solalyratin B, 3), together with three known compounds, puerariafuran (2), coumestrol (4) and 9-hydroxy-2',2'-dimethylpyrano[5',6':2,3]-coumestan (5), were isolated from the whole plant of Solanum lyratum. Their structures were elucidated on the basis of spectroscopic analyses. In vitro, compounds 1-5 showed anti-inflammatory activities, with IC(50) values in the range 6.3-9.1 μM.Entities:
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Year: 2011 PMID： 21898133 DOI： 10.1007/s11418-011-0581-3
Source DB: PubMed Journal: J Nat Med ISSN： 1340-3443 Impact factor: 2.343