Literature DB >> 2189748

Serum thymic factor as a radioprotective agent promoting survival after X-irradiation.

H Kobayashi1, H Abe, A Awaya, H Inano, M Shikita.   

Abstract

Serum thymic factor (FTS, zinc-free thymulin) protected mice from death after whole-body X-irradiation. It was significantly radioprotective even when administered after irradiation, but it was more effective when administered both before and after irradiation. The protective effect appears to be due to the enhancement of hematologic recovery in the animals.

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Year:  1990        PMID： 2189748     DOI： 10.1007/bf01954239

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  Use of recombinant granulocyte-macrophage colony stimulating factor in the Brazil radiation accident.

Authors:  A Butturini; P C De Souza; R P Gale; J M Cordiero; D M Lopes; C Neto; C B Cunha; C E De Souza; W G Ho; D G Tabak
Journal:  Lancet       Date:  1988-08-27       Impact factor: 79.321

2.  Radioprotection of hemopoiesis conferred by Acanthopanax senticosus Harms (Shigoka) administered before or after irradiation.

Authors:  T Miyanomae; E Frindel
Journal:  Exp Hematol       Date:  1988-10       Impact factor: 3.084

3.  Biochemical characterisation of a serum thymic factor.

Authors:  J Bach; M Bardenne; J Pleau; J Rosa
Journal:  Nature       Date:  1977-03-03       Impact factor: 49.962

4.  Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor.

Authors:  R Neta; J J Oppenheim; S D Douches
Journal:  J Immunol       Date:  1988-01-01       Impact factor: 5.422

5.  Increase of survival of X-irradiated mice by postirradiation injections of a splenic extract prepared from vaccine or endotoxin-treated syngenic animals.

Authors:  K Tsuneoka; Y Takagi; M Shikita
Journal:  J Radiat Res       Date:  1977-05       Impact factor: 2.724

6.  Suppression of acute experimental allergic encephalomyelitis by synthetic serum thymic factor. Clinical, histopathological, and immunohistochemical studies.

Authors:  S Kato; H Nakamura
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

7.  Contribution of zinc and other metals to the biological activity of the serum thymic factor.

Authors:  M Dardenne; J M Pléau; B Nabarra; P Lefrancier; M Derrien; J Choay; J F Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

8.  Intensive suppression of experimental allergic encephalomyelitis (EAE) by serum thymic factor and therapeutic implication for multiple sclerosis.

Authors:  Y Nagai; T Osanai; K Sakakibara
Journal:  Jpn J Exp Med       Date:  1982-08

9.  Endotoxin protection and colony-forming units.

Authors:  G E Hanks; E J Ainsworth
Journal:  Radiat Res       Date:  1967-11       Impact factor: 2.841

10.  Cytokines in therapy of radiation injury.

Authors:  R Neta; J J Oppenheim
Journal:  Blood       Date:  1988-09       Impact factor: 22.113
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  1 in total

1.  Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model.

Authors:  Leoni Villano Bonamin; Cesar Sato; Ruggero Zalla Neto; Graziela Morante; Thayná Neves Cardoso; Fabiana Rodrigues de Santana; Cideli de Paula Coelho; Lika Osugui; Ana Flavia Popi; Elizabeth Cristina Perez Hurtado; Mario Mariano
Journal:  Evid Based Complement Alternat Med       Date:  2013-01-28       Impact factor: 2.629
  1 in total

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