Literature DB >> 21894537

An Auxetic structure configured as oesophageal stent with potential to be used for palliative treatment of oesophageal cancer; development and in vitro mechanical analysis.

Murtaza N Ali1, Ihtesham Ur Rehman.   

Abstract

Oesophageal cancer is the ninth leading cause of malignant cancer death and its prognosis remains poor. Dysphagia which is an inability to swallow is a presenting symptom of oesophageal cancer and is indicative of incurability. The goal of this study was to design and manufacture an Auxetic structure film and to configure this film as an Auxetic stent for the palliative treatment of oesophageal cancer, and for the prevention of dysphagia. Polypropylene was used as a material for its flexibility and non-toxicity. The Auxetic (rotating-square geometry) structure was made by laser cutting the polypropylene film. This flat structure was welded together to form a tubular form (stent), by an adjustable temperature control soldering iron station: following this, an annealing process was also carried out to ease any material stresses. Poisson's ratio was estimated and elastic and plastic deformation of the Auxetic structure was evaluated. The elastic and plastic deformation behaviours of the Auxetic polypropylene film were evaluated by applying repetitive uniaxial tensile loads. Observation of the structure showed that it was initially elastically deformed, thereafter plastic deformation occurred. This research discusses a novel way of fabricating an Auxetic structure (rotating-squares connected together through hinges) on Polypropylene films, by estimating the Poisson's ratio and evaluating the plastic deformation relevant to the expansion behaviour of an Auxetic stent within the oesophageal lumen.

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Year:  2011        PMID: 21894537     DOI: 10.1007/s10856-011-4436-y

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN: 0957-4530            Impact factor:   3.896


  15 in total

Review 1.  Esophageal cancer.

Authors:  Eric Elton
Journal:  Dis Mon       Date:  2005-12       Impact factor: 3.800

Review 2.  An update in the palliative management of malignant dysphagia.

Authors:  A K Kubba; N Krasner
Journal:  Eur J Surg Oncol       Date:  2000-03       Impact factor: 4.424

3.  Self-expandable coated stent after intraluminal treatment of esophageal cancer: a risky procedure?

Authors:  A Maier; H Pinter; G B Friehs; H Renner; F M Smolle-Jüttner
Journal:  Ann Thorac Surg       Date:  1999-03       Impact factor: 4.330

4.  Are self-expanding metal mesh stents useful in the treatment of benign esophageal stenoses and fistulas? An experience of four cases.

Authors:  J G Lee; R Hsu; J W Leung
Journal:  Am J Gastroenterol       Date:  2000-08       Impact factor: 10.864

5.  Comparative study of self-expandable metallic stent and bypass surgery for inoperable esophageal cancer.

Authors:  T Aoki; Y Osaka; Y Takagi; R Okada; M Shinohara; A Tsuchida; S Sato; Y Koyanagi
Journal:  Dis Esophagus       Date:  2001       Impact factor: 3.429

6.  Palliation of Dysphagia of Esophageal Cancer by Endoscopic Lumen Restoration Techniques.

Authors: 
Journal:  Cancer Control       Date:  1999-01       Impact factor: 3.302

Review 7.  Use of the Polyflex stent in the palliative therapy of esophageal carcinoma: results in 14 cases and review of the literature.

Authors:  P Decker; J Lippler; D Decker; A Hirner
Journal:  Surg Endosc       Date:  2001-12       Impact factor: 4.584

Review 8.  Use of metallic stents and balloons in the esophagus and gastrointestinal tract.

Authors:  R Morgan; A Adam
Journal:  J Vasc Interv Radiol       Date:  2001-03       Impact factor: 3.464

9.  Palliation of malignant esophageal obstruction due to intrinsic and extrinsic lesions with expandable metal stents.

Authors:  N Bethge; A Sommer; N Vakil
Journal:  Am J Gastroenterol       Date:  1998-10       Impact factor: 10.864

10.  Are metal stents effective for palliation of malignant dysphagia and fistulas?

Authors:  P P Kostopoulos; M I Zissis; A A Polydorou; P P Premchand; M T Hendrickse; C J Shorrock; P E T Isaacs
Journal:  Dig Liver Dis       Date:  2003-04       Impact factor: 4.088

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  3 in total

1.  Auxetic oesophageal stents: structure and mechanical properties.

Authors:  Murtaza Najabat Ali; James J C Busfield; Ihtesham U Rehman
Journal:  J Mater Sci Mater Med       Date:  2013-10-20       Impact factor: 3.896

Review 2.  Cellular Auxetic Structures for Mechanical Metamaterials: A Review.

Authors:  Parth Uday Kelkar; Hyun Soo Kim; Kyung-Hoon Cho; Joon Young Kwak; Chong-Yun Kang; Hyun-Cheol Song
Journal:  Sensors (Basel)       Date:  2020-06-01       Impact factor: 3.576

3.  Filtration Properties of Auxetics with Rotating Rigid Units.

Authors:  Daphne Attard; Aaron R Casha; Joseph N Grima
Journal:  Materials (Basel)       Date:  2018-05-03       Impact factor: 3.623

  3 in total

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