Literature DB >> 21894335

One-pot synthesis of pyrrolo[1,2-a]quinoxalines.

Aiping Huang1, Feng Liu, Chunjing Zhan, Yanli Liu, Chen Ma.   

Abstract

A transition metal-free process for the regioselective synthesis of pyrrolo[1,2-a]quinoxalines under mild conditions in one-pot is described. The reaction afforded a variety of products in good to excellent yields. Indolo[1,2-a]quinoxalines were also synthesized from indole-2-carboxamides under the same conditions.

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Year:  2011        PMID: 21894335     DOI: 10.1039/c1ob05936j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  6 in total

1.  Synthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-α]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence.

Authors:  Sarah M Scarry; Kimberly M Lovell; Kevin J Frankowski; Laura M Bohn; Jeffrey Aubé
Journal:  J Org Chem       Date:  2016-08-02       Impact factor: 4.354

Review 2.  Transition metal-free one-pot synthesis of nitrogen-containing heterocycles.

Authors:  Simpal Kumari; Dharma Kishore; Sarvesh Paliwal; Rajani Chauhan; Jaya Dwivedi; Aakanksha Mishra
Journal:  Mol Divers       Date:  2015-06-09       Impact factor: 2.943

3.  Electrophotocatalytic SN Ar Reactions of Unactivated Aryl Fluorides at Ambient Temperature and Without Base.

Authors:  He Huang; Tristan H Lambert
Journal:  Angew Chem Int Ed Engl       Date:  2019-11-22       Impact factor: 15.336

4.  α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction.

Authors:  Mayavan Viji; Manjunatha Vishwanath; Jaeuk Sim; Yunjeong Park; Chanhyun Jung; Seohu Lee; Heesoon Lee; Kiho Lee; Jae-Kyung Jung
Journal:  RSC Adv       Date:  2020-10-07       Impact factor: 4.036

5.  New highlights of the syntheses of pyrrolo[1,2-a]quinoxalin-4-ones.

Authors:  Emilian Georgescu; Alina Nicolescu; Florentina Georgescu; Florina Teodorescu; Daniela Marinescu; Ana-Maria Macsim; Calin Deleanu
Journal:  Beilstein J Org Chem       Date:  2014-10-14       Impact factor: 2.883

6.  Tertiary amine-directed and involved carbonylative cyclizations through Pd/Cu-cocatalyzed multiple C-X (X = H or N) bond cleavage.

Authors:  Qiu-Chao Mu; Yi-Xue Nie; Xing-Feng Bai; Jing Chen; Lei Yang; Zheng Xu; Li Li; Chun-Gu Xia; Li-Wen Xu
Journal:  Chem Sci       Date:  2019-08-19       Impact factor: 9.825

  6 in total

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