Literature DB >> 21894254

Photoletter to the editor: Oral ulceration in pyoderma gangrenosum.

Saroj Verma1, Sinead Field, Gillian Murphy.   

Abstract

A 65-year-old woman presented with widespread necrotising cutaneous ulceration and oral involvement. Past history included rheumatoid arthritis, and a left nephrectomy.Examination revealed multiple violaceous undermined ulcers. Blood investigations showed an acute inflammatory response. Skin histopathology showed epidermal ulceration with acute and chronic inflammation. Direct immunofluorescence was negative. A diagnosis of pyoderma gangrenosum with oral involvement was made. Mycophenolate mofetil therapy resulted in complete resolution of her pyoderma gangrenosum. Her treatment was complicated by a left proteus mirabilis psoas abscess. This resolved following four weeks of antibiotics.Pyoderma gangrenosum with oral involvement is rare but has been linked with inflammatory bowel disease and hematological disorders. Oral pyoderma gangrenosum has not previously been described in rheumatoid arthritis. Primary psoas abscess is rare but can develop in immunocompromised patients. Proteus mirabilis has been reported in patients years after nephrectomy. This is a rare case of pyoderma gangrenosum with oral involvement.

Entities:  

Keywords:  mycophenolate mofetil; oral mucosa; oral ulceration; psoas abscess; pyoderma gangrenosum

Year:  2011        PMID: 21894254      PMCID: PMC3163356          DOI: 10.3315/jdcr.2011.1070

Source DB:  PubMed          Journal:  J Dermatol Case Rep        ISSN: 1898-7249


  5 in total

1.  Oral pyoderma gangrenosum.

Authors:  A Hernández-Martín; D Arias-Palomo; G Hermida; M C Gutiérrez-Ortega; M Ramírez-Herrera; M Rodríguez-Vegas; A Velasco
Journal:  Br J Dermatol       Date:  2003-09       Impact factor: 9.302

Review 2.  Iliopsoas abscesses.

Authors:  I H Mallick; M H Thoufeeq; T P Rajendran
Journal:  Postgrad Med J       Date:  2004-08       Impact factor: 2.401

3.  Mycophenolate mofetil as therapy for pyoderma gangrenosum.

Authors:  Philip A Eaton; Jeffrey P Callen
Journal:  Arch Dermatol       Date:  2009-07

4.  Iliopsoas abscess: a re-emerging clinical entity not to be forgotten.

Authors:  Z Al-Hilli; R S Prichard; G Roche-Nagle; J Deasy; D A McNamara
Journal:  Ir Med J       Date:  2009-02

Review 5.  Pyoderma gangrenosum with oral involvement - case report and review of the literature.

Authors:  Geetha Paramkusam; Venkateswarlu Meduri; Naresh Gangeshetty
Journal:  Int J Oral Sci       Date:  2010-06       Impact factor: 6.344

  5 in total
  2 in total

Review 1.  Oral Pyoderma Gangrenosum: Diagnosis, Treatment and Challenges: A Systematic Review.

Authors:  Caroline Bissonnette; Adel Kauzman; Gisele N Mainville
Journal:  Head Neck Pathol       Date:  2017-03-08

2.  Photoletter to the editor: Localized pyoderma gangrenosum after interferon-alpha2b injections.

Authors:  José M Mir-Bonafé; Susana Blanco-Barrios; Alberto Romo-Melgar; Angel Santos-Briz; Emilia Fernández-López
Journal:  J Dermatol Case Rep       Date:  2012-09-28
  2 in total

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