Literature DB >> 21894095

Effect of tianeptine on cognitive functions in patients with depressive disorders during a 3-month observation.

Adam Klasik1, Krzysztof Krysta, Irena Krupka-Matuszczyk.   

Abstract

OBJECTIVE: The authors put forward the hypotheses that during a three-month treatment with tianeptine in patients with depressive disorders there is an improvement in the short-term memory, reaction time and attention. SUBJECT AND METHODS: 20 patients suffering from depression, were included in the study. During the entire research period all patients were treated with monotherapy with tianeptine. Cognitive function measurements were performed using the Vienna Test System.
RESULTS: Our study showed an improvement in the all the assessed functions: patients treated with tianeptine had better performance in tests measuring short term memory and learning processes as well as reaction time and attention.
CONCLUSION: In conclusion, the study shows that tianeptine improves cognitive functions in depressed patients.

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Year:  2011        PMID: 21894095

Source DB:  PubMed          Journal:  Psychiatr Danub        ISSN: 0353-5053            Impact factor:   1.063


  5 in total

Review 1.  Impact of pharmacological and psychological treatment methods of depressive and anxiety disorders on cognitive functioning.

Authors:  Krzysztof Krysta; Marek Krzystanek; Małgorzata Janas-Kozik; Adam Klasik; Irena Krupka-Matuszczyk
Journal:  J Neural Transm (Vienna)       Date:  2014-07-31       Impact factor: 3.575

2.  Pharmacokinetic study of tianeptine and its active metabolite MC5 in rats following different routes of administration using a novel liquid chromatography tandem mass spectrometry analytical method.

Authors:  Małgorzata Szafarz; Agnieszka Wencel; Krzysztof Pociecha; Filip A Fedak; Piotr Wlaź; Elżbieta Wyska
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2017-12-12       Impact factor: 3.000

3.  Modulation of atypical brain activation during executive functioning in autism: a pharmacological MRI study of tianeptine.

Authors:  Robert H Wichers; James L Findon; Auke Jelsma; Vincent Giampietro; Vladimira Stoencheva; Dene M Robertson; Clodagh M Murphy; Sarah Blainey; Grainne McAlonan; Christine Ecker; Katya Rubia; Declan G M Murphy; Eileen M Daly
Journal:  Mol Autism       Date:  2021-02-19       Impact factor: 7.509

Review 4.  Cognitive remission: a novel objective for the treatment of major depression?

Authors:  Beatrice Bortolato; Kamilla W Miskowiak; Cristiano A Köhler; Michael Maes; Brisa S Fernandes; Michael Berk; André F Carvalho
Journal:  BMC Med       Date:  2016-01-22       Impact factor: 8.775

Review 5.  Influence of Pharmacotherapy on Cognitive Functions in Depression: A Review of the Literature.

Authors:  Agata Orzechowska; Maria Filip; Piotr Gałecki
Journal:  Med Sci Monit       Date:  2015-11-24
  5 in total

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