Literature DB >> 21892388

Efficacy of unipedicular baloon kyphoplasty for treatment of multiple myeloma vertebral lesions.

Giovanni Andrea La Maida1, Francesco Sala, Giovanna Callea, Dario Capitani, Saurabh Singh.   

Abstract

STUDY
DESIGN: A retrospective cohort study.
PURPOSE: To analyze differences in between the unipedicular vs. bipedicular balloon kyphoplasty for the treatment of multiple myeloma lesions. OVERVIEW OF LITERATURE: Both vertebroplasty and kyphoplasty are reported to be effective for the treatment of vertebral compression fractures in multiple myeloma patients. Kyphoplasty is often performed with a bipedicular approach while vertebroplasty with a monopedicular approach. Monopedicular kyphoplasty is investigated as a viable surgical technique alternatively in comparison with the bipedicular method.
METHODS: We performed 37 vertebral body augmentation procedures, 18 vertebroplasty (group A) and 19 kyphoplasty, 9 unipedicular approaches (group B1) and 10 bipedicular approaches (group B2), on 14 patients affected by multiple myeloma with a mean clinical and radiographic follow up of more than 12 months.
RESULTS: Both kyphoplasty techniques lead to a better postoperative improvement of the vertebral height and kyphotic deformity if compared with the vertebroplasty, with a statistical significance for the body height restoration only (p = 0.0066). The unipedicular and the bipedicular kyphoplasty have similar results in term of kyphotic deformity correction and height restoration. The 85.7% (12/14) of the patients had an immediate improvement of the pain and no difference between the vertebroplasty and kyphoplasty groups were observed regarding the pain. We observed a 24.3% of cement leakage in all groups with no clinical symptoms and noticed that the risk of extravasations was higher in multilevel treatment, in bipedicular kyphoplasty procedures and in patients not treated previously with a bone marrow transplant.
CONCLUSIONS: Both vertebroplasty and kyphoplasty are effective in treating vertebral compression fracture due to multiple myeloma. Unipedicular kyphoplasty could give equivalent results as with bipedicular kyphoplasty in multilevel disease, aiming only to restore the sagittal alignment of the spine and the height of the vertebral body especially at the thoracolumbar spinal segment.

Entities:  

Keywords:  Kyphoplasty; Multiple myeloma; Unipedicular; Vertebroplasty

Year:  2011        PMID: 21892388      PMCID: PMC3159064          DOI: 10.4184/asj.2011.5.3.162

Source DB:  PubMed          Journal:  Asian Spine J        ISSN: 1976-1902


  27 in total

1.  Preliminary study on a single balloon cross-midline expansion via unipedicular approach in kyphoplasty.

Authors:  Gang Sun; Peng Jin; Fan-dong Li; Xun-wei Liu; Run-song Hao; Yu-hai Yi; Zhi-yong Xie
Journal:  Chin Med J (Engl)       Date:  2008-09-20       Impact factor: 2.628

2.  Initial outcome and efficacy of "kyphoplasty" in the treatment of painful osteoporotic vertebral compression fractures.

Authors:  I H Lieberman; S Dudeney; M K Reinhardt; G Bell
Journal:  Spine (Phila Pa 1976)       Date:  2001-07-15       Impact factor: 3.468

3.  Kyphoplasty in the treatment of osteolytic vertebral compression fractures as a result of multiple myeloma.

Authors:  S Dudeney; I H Lieberman; M-K Reinhardt; M Hussein
Journal:  J Clin Oncol       Date:  2002-05-01       Impact factor: 44.544

4.  Comparative study of balloon kyphoplasty with unilateral versus bilateral approach in osteoporotic vertebral compression fractures.

Authors:  Hyung Jin Chung; Kook Jin Chung; Hoi Soo Yoon; In Hyup Kwon
Journal:  Int Orthop       Date:  2007-09-03       Impact factor: 3.075

5.  Trends in pathological vertebral fractures in the United States: 1993 to 2004.

Authors:  Shivanand P Lad; Chirag G Patil; Eleonora Maries Lad; Maxwell Boakye
Journal:  J Neurosurg Spine       Date:  2007-09

6.  Unipedicular balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures: early results.

Authors:  Elias C Papadopoulos; Folorunsho Edobor-Osula; Michael J Gardner; Michael K Shindle; Joseph M Lane
Journal:  J Spinal Disord Tech       Date:  2008-12

7.  Percutaneous vertebroplasty in multiple myeloma vertebral involvement.

Authors:  Salvatore Masala; Giovanni Carlo Anselmetti; Stefano Marcia; Francesco Massari; Antonio Manca; Giovanni Simonetti
Journal:  J Spinal Disord Tech       Date:  2008-07

8.  [Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty].

Authors:  P Galibert; H Deramond; P Rosat; D Le Gars
Journal:  Neurochirurgie       Date:  1987       Impact factor: 1.553

9.  An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplasty.

Authors:  Frank M Phillips; F Todd Wetzel; Isadore Lieberman; Marrion Campbell-Hupp
Journal:  Spine (Phila Pa 1976)       Date:  2002-10-01       Impact factor: 3.468

10.  Balloon kyphoplasty in the treatment of metastatic disease of the spine: a 2-year prospective evaluation.

Authors:  R Pflugmacher; R Taylor; A Agarwal; I Melcher; A Disch; N P Haas; C Klostermann
Journal:  Eur Spine J       Date:  2008-06-17       Impact factor: 3.134

View more
  7 in total

1.  Cement leakage: safety of minimally invasive surgical techniques in the treatment of multiple myeloma vertebral lesions.

Authors:  Giovanni Andrea La Maida; Laura Serena Giarratana; Alberto Acerbi; Valentina Ferrari; Giuseppe Vincenzo Mineo; Bernardo Misaggi
Journal:  Eur Spine J       Date:  2012-03-13       Impact factor: 3.134

2.  Efficacy and Safety of Balloon Kyphoplasty for Pathological Vertebral Fractures in Patients with Hematological Malignancies in Our Institution.

Authors:  Keigo Okada; Hiroki Fujiwara; Tomoyuki Arimatsu; Yotaro Motomura; Tsuyoshi Kato; Naoki Takezako; Takashi Kumagai
Journal:  Intern Med       Date:  2020-11-23       Impact factor: 1.271

3.  Unipedicular baloon kyphoplasty.

Authors:  Viroj Wiwanitkit
Journal:  Asian Spine J       Date:  2011-11-28

4.  Comparison if the addition of multilevel vertebral augmentation to conventional therapy will improve the outcome of patients with multiple myeloma.

Authors:  Ziad A Audat; Mahmoud H Hajyousef; Mohammad D Fawareh; Khaldoon M Alawneh; Mohannad A Odat; Mohammad M Barbarawi; Ali A Alomari; Rami A Jahmani; Mohammad A Khatatbeh; Mohammed A Assmairan
Journal:  Scoliosis Spinal Disord       Date:  2016-12-29

5.  Open kyphoplasty in the treatment of a painful vertebral lytic lesion with spinal cord compression caused by multiple myeloma: A case report.

Authors:  Jun Pan; Zhong-Lai Qian; Zhi-Yong Sun; Hui-Lin Yang
Journal:  Oncol Lett       Date:  2013-03-01       Impact factor: 2.967

6.  Vertebral augmentation in the treatment of pathologic compression fractures in 792 patients with multiple myeloma.

Authors:  E Erdem; R Samant; S F Malak; W C Culp; A Brown; L Peterson; S Lensing; B Barlogie
Journal:  Leukemia       Date:  2013-06-03       Impact factor: 11.528

7.  Comparison of Unilateral versus Bilateral Kyphoplasty in Multiple Myeloma Patients and the Importance of Preoperative Planning.

Authors:  Ioannis D Papanastassiou; Mohamed Eleraky; Ryan Murtagh; Zinon T Kokkalis; Maria Gerochristou; Frank D Vrionis
Journal:  Asian Spine J       Date:  2014-06-09
  7 in total

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