Literature DB >> 21890215

No association of polymorphisms in the CDK5, NDEL1, and LIS1 with autism in Chinese Han population.

Lifang Wang1, Jun Li, Meixiang Jia, Weihua Yue, Yanyan Ruan, Tianlan Lu, Jishui Zhang, Jing Liu, Dai Zhang.   

Abstract

Autism is a pervasive neurodevelopmental disorder. CDK5 (cyclin-dependent kinase 5) and its interacting molecules are involved in neurodevelopment. We performed a family-based association analysis between CDK5, NDEL1, and LIS1 polymorphisms and autism in a Chinese Han population. Our study did not detect a significant association. It indicated that common genetic variations in these genes might not play a role in the genetic predisposition to autism.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21890215     DOI: 10.1016/j.psychres.2011.08.004

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  1 in total

1.  Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue.

Authors:  Balmiki Ray; Deborah K Sokol; Bryan Maloney; Debomoy K Lahiri
Journal:  Sci Rep       Date:  2016-05-23       Impact factor: 4.379

  1 in total

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