Literature DB >> 21889310

Multivariate graphical methods provide an insightful way to formulate explanatory hypotheses from limited categorical data.

Peter H Van Ness1, Terrence E Murphy, Katy L B Araujo, Margaret A Pisani.   

Abstract

OBJECTIVE: Graphical methods for generating explanatory hypotheses from limited categorical data are described and illustrated. STUDY DESIGN AND
SETTING: Univariate, bivariate, multivariate, and multiplicative graphical methods were applied to clinical data regarding very ill older persons. The data to which these methods were applied were limited as to their nature (e.g., nominal categorical data) or quality (e.g., data subject to measurement error and missing values). Such limitations make confirmatory inference problematic but might still allow for meaningful generation of new explanatory hypotheses in some cases.
RESULTS: A striking feature of the graphical results from this study's major illustrative application was that posttraumatic stress disorder (PTSD) after intensive care unit discharge occurred rarely and nearly always co-occurred with two or more other mental health conditions. These results suggest the explanatory hypothesis that PTSD in this context is less attributable to single traumatic causes than to acute illnesses contributing to a cascade of mental health decrements.
CONCLUSION: Illustrative applications of a sequence of graphical procedures yield more informative and less abstract representations of limited data than do descriptive statistics alone, and by doing so, they aid in the formulation of explanatory hypotheses.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21889310      PMCID: PMC3250573          DOI: 10.1016/j.jclinepi.2011.06.007

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


  10 in total

1.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.

Authors:  M F Folstein; S E Folstein; P R McHugh
Journal:  J Psychiatr Res       Date:  1975-11       Impact factor: 4.791

2.  Case-finding instruments for depression. Two questions are as good as many.

Authors:  M A Whooley; A L Avins; J Miranda; W S Browner
Journal:  J Gen Intern Med       Date:  1997-07       Impact factor: 5.128

3.  Changes in depression and physical decline in older adults: a longitudinal perspective.

Authors:  B W Penninx; D J Deeg; J T van Eijk; A T Beekman; J M Guralnik
Journal:  J Affect Disord       Date:  2000-12       Impact factor: 4.839

4.  Prospective study of health status preferences and changes in preferences over time in older adults.

Authors:  Terri R Fried; Amy L Byers; William T Gallo; Peter H Van Ness; Virginia R Towle; John R O'Leary; Joel A Dubin
Journal:  Arch Intern Med       Date:  2006-04-24

5.  STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION.

Authors:  S KATZ; A B FORD; R W MOSKOWITZ; B A JACKSON; M W JAFFE
Journal:  JAMA       Date:  1963-09-21       Impact factor: 56.272

6.  Clarifying confusion: the confusion assessment method. A new method for detection of delirium.

Authors:  S K Inouye; C H van Dyck; C A Alessi; S Balkin; A P Siegal; R I Horwitz
Journal:  Ann Intern Med       Date:  1990-12-15       Impact factor: 25.391

7.  Sensitivity and specificity of a screening test to document traumatic experiences and to diagnose post-traumatic stress disorder in ARDS patients after intensive care treatment.

Authors:  C Stoll; H P Kapfhammer; H B Rothenhäusler; M Haller; J Briegel; M Schmidt; T Krauseneck; K Durst; G Schelling
Journal:  Intensive Care Med       Date:  1999-07       Impact factor: 17.440

8.  The impact of depressive symptomatology on physical disability: MacArthur Studies of Successful Aging.

Authors:  M L Bruce; T E Seeman; S S Merrill; D G Blazer
Journal:  Am J Public Health       Date:  1994-11       Impact factor: 9.308

9.  Correspondence analysis is a useful tool to uncover the relationships among categorical variables.

Authors:  Nadia Sourial; Christina Wolfson; Bin Zhu; Jacqueline Quail; John Fletcher; Sathya Karunananthan; Karen Bandeen-Roche; François Béland; Howard Bergman
Journal:  J Clin Epidemiol       Date:  2009-11-06       Impact factor: 6.437

10.  Characteristics associated with delirium in older patients in a medical intensive care unit.

Authors:  Margaret A Pisani; Terrence E Murphy; Peter H Van Ness; Katy L B Araujo; Sharon K Inouye
Journal:  Arch Intern Med       Date:  2007 Aug 13-27
  10 in total

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