Literature DB >> 21888972

Expert opinion: Responsive polymer nanoparticles in cancer therapy.

William B Liechty1, Nicholas A Peppas.   

Abstract

Polymeric nanoparticles are emerging as an attractive treatment options for cancer due to their favorable size distribution, drug carrying capacity, and tunable properties. In particular, intelligent nanoparticles that respond to biological cues are of interest because of their ability to provide controlled release at a specific site. Tumor sites display abnormal pH profiles and pathophysiology that can be exploited to provide localized release. In this expert opinion, we discuss passive and active targeting of nanoparticles and several classes of pH-responsive nanoparticles.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID： 21888972      PMCID： PMC3269567          DOI： 10.1016/j.ejpb.2011.08.004

Source DB:  PubMed          Journal:  Eur J Pharm Biopharm        ISSN： 0939-6411            Impact factor:   5.571


  46 in total

Review 1.  Intelligent therapeutics: biomimetic systems and nanotechnology in drug delivery.

Authors:  Nicholas A Peppas
Journal:  Adv Drug Deliv Rev       Date:  2004-09-22       Impact factor: 15.470

Review 2.  Is the oral route possible for peptide and protein drug delivery?

Authors:  Mariko Morishita; Nicholas A Peppas
Journal:  Drug Discov Today       Date:  2006-09-07       Impact factor: 7.851

3.  Shape effects of filaments versus spherical particles in flow and drug delivery.

Authors:  Yan Geng; Paul Dalhaimer; Shenshen Cai; Richard Tsai; Manorama Tewari; Tamara Minko; Dennis E Discher
Journal:  Nat Nanotechnol       Date:  2007-03-25       Impact factor: 39.213

Review 4.  Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles.

Authors:  Donald E Owens; Nicholas A Peppas
Journal:  Int J Pharm       Date:  2005-11-21       Impact factor: 5.875

Review 5.  Polymers for drug delivery systems.

Authors:  William B Liechty; David R Kryscio; Brandon V Slaughter; Nicholas A Peppas
Journal:  Annu Rev Chem Biomol Eng       Date:  2010       Impact factor: 11.059

6.  Advanced molecular design of biopolymers for transmucosal and intracellular delivery of chemotherapeutic agents and biological therapeutics.

Authors:  William B Liechty; Mary Caldorera-Moore; Margaret A Phillips; Cody Schoener; Nicholas A Peppas
Journal:  J Control Release       Date:  2011-06-14       Impact factor: 9.776

7.  New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties.

Authors:  T Etrych; M Jelínková; B Ríhová; K Ulbrich
Journal:  J Control Release       Date:  2001-05-18       Impact factor: 9.776

Review 8.  Nanoparticle therapeutics: an emerging treatment modality for cancer.

Authors:  Mark E Davis; Zhuo Georgia Chen; Dong M Shin
Journal:  Nat Rev Drug Discov       Date:  2008-09       Impact factor: 84.694

9.  Enhanced core hydrophobicity, functionalization and cell penetration of polybasic nanomatrices.

Authors:  Omar Z Fisher; Timothy Kim; Stephen R Dietz; Nicholas A Peppas
Journal:  Pharm Res       Date:  2008-08-28       Impact factor: 4.200

10.  A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Authors:  Y Matsumura; H Maeda
Journal:  Cancer Res       Date:  1986-12       Impact factor: 12.701
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  43 in total

1.  PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy.

Authors:  Fereydoon Abedi-Gaballu; Gholamreza Dehghan; Maryam Ghaffari; Reza Yekta; Soheil Abbaspour-Ravasjani; Behzad Baradaran; Jafar Ezzati Nazhad Dolatabadi; Michael R Hamblin
Journal:  Appl Mater Today       Date:  2018-05-29

Review 2.  Nanoparticle Probes for the Detection of Cancer Biomarkers, Cells, and Tissues by Fluorescence.

Authors:  Alyssa B Chinen; Chenxia M Guan; Jennifer R Ferrer; Stacey N Barnaby; Timothy J Merkel; Chad A Mirkin
Journal:  Chem Rev       Date:  2015-08-27       Impact factor: 60.622

Review 3.  Engineering liposomal nanoparticles for targeted gene therapy.

Authors:  C Zylberberg; K Gaskill; S Pasley; S Matosevic
Journal:  Gene Ther       Date:  2017-05-15       Impact factor: 5.250

4.  Surface-modified P(HEMA-co-MAA) nanogel carriers for oral vaccine delivery: design, characterization, and in vitro targeting evaluation.

Authors:  Matilde Durán-Lobato; Brenda Carrillo-Conde; Yasmine Khairandish; Nicholas A Peppas
Journal:  Biomacromolecules       Date:  2014-07-02       Impact factor: 6.988

5.  Stimulus-responsive hydrogels: Theory, modern advances, and applications.

Authors:  Michael C Koetting; Jonathan T Peters; Stephanie D Steichen; Nicholas A Peppas
Journal:  Mater Sci Eng R Rep       Date:  2015-05-16       Impact factor: 36.214

6.  Intelligent Nanoparticles for Advanced Drug Delivery in Cancer Treatment.

Authors:  David S Spencer; Amey S Puranik; Nicholas A Peppas
Journal:  Curr Opin Chem Eng       Date:  2015-02       Impact factor: 5.163

Review 7.  Exploiting homing abilities of cell carriers: Targeted delivery of nanoparticles for cancer therapy.

Authors:  Pamela Tiet; Jacob M Berlin
Journal:  Biochem Pharmacol       Date:  2017-09-21       Impact factor: 5.858

8.  Intelligent recognitive systems in nanomedicine.

Authors:  Heidi Culver; Adam Daily; Ali Khademhosseini; Nicholas Peppas
Journal:  Curr Opin Chem Eng       Date:  2014-05-01       Impact factor: 5.163

9.  Transport and delivery of interferon-α through epithelial tight junctions via pH-responsive poly(methacrylic acid-grafted-ethylene glycol) nanoparticles.

Authors:  Mary Caldorera-Moore; Julia E Vela Ramirez; Nicholas A Peppas
Journal:  J Drug Target       Date:  2019-03-01       Impact factor: 5.121

10.  Co-delivery of siRNA and therapeutic agents using nanocarriers to overcome cancer resistance.

Authors:  Mar Creixell; Nicholas A Peppas
Journal:  Nano Today       Date:  2012-08-01       Impact factor: 20.722
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