J-O Park1, C-K Jung, D-I Sun, M-S Kim. 1. Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Abstract
BACKGROUND: Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity. CASE REPORT: A 36-year-old woman presented with a mass in her left nasal cavity. Histopathological evaluation revealed it to be an epithelial-myoepithelial carcinoma with overt nuclear atypia, frequent mitoses and necrosis. The tumour recurred in the contralateral nasal cavity 15 months following primary excision. Medial maxillectomy and radiation therapy were performed. Seven-month follow up revealed extensive bone metastases. CONCLUSION: We report a rare case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity, with high-grade histology.
BACKGROUND:Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity. CASE REPORT: A 36-year-old woman presented with a mass in her left nasal cavity. Histopathological evaluation revealed it to be an epithelial-myoepithelial carcinoma with overt nuclear atypia, frequent mitoses and necrosis. The tumour recurred in the contralateral nasal cavity 15 months following primary excision. Medial maxillectomy and radiation therapy were performed. Seven-month follow up revealed extensive bone metastases. CONCLUSION: We report a rare case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity, with high-grade histology.
Authors: Theodore A Schuman; Adam J Kimple; Claire H Edgerly; Charles S Ebert; Adam M Zanation; Brian D Thorp Journal: Allergy Rhinol (Providence) Date: 2018-04-09