Literature DB >> 21887389

Surgical results of unruptured intracranial aneurysms in the elderly : single center experience in the past ten years.

Young Jin Jung1, Jae Sung Ahn, Eun Suk Park, Do Hoon Kwon, Byung Duk Kwun, Chang Jin Kim.   

Abstract

OBJECTIVE: As medical advances have increased life expectancy, it has become imperative to develop specific treatment strategies for intracranial aneurysms in the elderly. We therefore analyzed the clinical characteristics and outcomes of the treatment of unruptured intracranial aneurysms in patients older than 70 years.
METHODS: We retrospectively reviewed the medical records and results of neuroimaging modalities on 54 aneurysms of 48 consecutive patients with unruptured intracranial aneurysms. (mean±SD age, 72.11±1.96 years; range, 70-78 years) who underwent surgical clipping over 10 years (May 1999 to June 2010).
RESULTS: Of the 54 aneurysms, 22 were located in the internal carotid artery, 19 in the middle cerebral artery, 12 in the anterior cerebral artery, and 1 in the superior cerebellar artery. Six patients had multiple aneurysms. Aneurysm size ranged from 3 mm to 17 mm (mean±SD, 6.82±3.07 mm). Fifty of the 54 aneurysms (92.6%) were completely clipped. Three-month outcomes were excellent in 50 (92.6%) aneurysms and good and poor in 2 each (3.7%), with 1 death (2.0%). Procedure-related complications occurred in 7 aneurysms (13.0%), with 2 (3.7%) resulting in permanent neurological deficits, including death. No postoperative subarachnoid hemorrhage occurred during follow-up. The cumulative rates of stroke- or death-free survival at 5 and 10 years were 100% and 78%, respectively.
CONCLUSION: Surgical clipping of unruptured intracranial aneurysms in elderly group could get it as a favorable outcome in well selected cases.

Entities:  

Keywords:  Elderly; Outcome; Surgical clipping; Unruptured intracranial aneurysm

Year:  2011        PMID: 21887389      PMCID: PMC3158474          DOI: 10.3340/jkns.2011.49.6.329

Source DB:  PubMed          Journal:  J Korean Neurosurg Soc        ISSN: 1225-8245


  20 in total

1.  Simulation of the natural history of cerebral aneurysms based on data from the International Study of Unruptured Intracranial Aneurysms.

Authors:  Han Soo Chang
Journal:  J Neurosurg       Date:  2006-02       Impact factor: 5.115

2.  Endovascular treatment of intracranial aneurysms in the elderly: single-center experience in 63 consecutive patients.

Authors:  Yiling Cai; Laurent Spelle; Huan Wang; Michel Piotin; Charbel Mounayer; José Ricardo Vanzin; Jacques Moret
Journal:  Neurosurgery       Date:  2005-12       Impact factor: 4.654

Review 3.  Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review.

Authors:  J W Hop; G J Rinkel; A Algra; J van Gijn
Journal:  Stroke       Date:  1997-03       Impact factor: 7.914

4.  Morbidity and mortality from surgical treatment of unruptured cerebral aneurysms at Research Institute for Brain and Blood Vessels-Akita.

Authors:  Junta Moroi; Hiromu Hadeishi; Akifumi Suzuki; Nobuyuki Yasui
Journal:  Neurosurgery       Date:  2005-02       Impact factor: 4.654

Review 5.  Risk of rupture associated with intact cerebral aneurysms in the Japanese population: a systematic review of the literature from Japan.

Authors:  Akio Morita; Satoru Fujiwara; Kazuo Hashi; Hiroshi Ohtsu; Takaaki Kirino
Journal:  J Neurosurg       Date:  2005-04       Impact factor: 5.115

6.  Subarachnoid and intracerebral hemorrhage: natural history, prognosis, and precursive factors in the Framingham Study.

Authors:  R L Sacco; P A Wolf; N E Bharucha; S L Meeks; W B Kannel; L J Charette; P M McNamara; E P Palmer; R D'Agostino
Journal:  Neurology       Date:  1984-07       Impact factor: 9.910

7.  The unchanging pattern of subarachnoid hemorrhage in a community.

Authors:  L H Phillips; J P Whisnant; W M O'Fallon; T M Sundt
Journal:  Neurology       Date:  1980-10       Impact factor: 9.910

8.  Unruptured intracranial aneurysms in elderly patients.

Authors:  T Inagawa; H Hada; Y Katoh
Journal:  Surg Neurol       Date:  1992-11

Review 9.  Guidelines for the surgical treatment of unruptured intracranial aneurysms: the first annual J. Lawrence pool memorial research symposium--controversies in the management of cerebral aneurysms.

Authors:  Ricardo J Komotar; J Mocco; Robert A Solomon
Journal:  Neurosurgery       Date:  2008-01       Impact factor: 4.654

10.  Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study.

Authors:  N J Solenski; E C Haley; N F Kassell; G Kongable; T Germanson; L Truskowski; J C Torner
Journal:  Crit Care Med       Date:  1995-06       Impact factor: 7.598

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  2 in total

Review 1.  Endovascular and Surgical Treatment of Unruptured MCA Aneurysms: Meta-Analysis and Review of the Literature.

Authors:  Spiros L Blackburn; Abdelrahman M Abdelazim; Andrew B Cutler; Kevin T Brookins; Kyle M Fargen; Brian L Hoh; Yasha Kadkhodayan
Journal:  Stroke Res Treat       Date:  2014-04-01

2.  Clipping of unruptured cerebral aneurysms : Are older patients at higher risk?

Authors:  Fabian Winter; Celia M Markert; Maximilian Krawagna; Michael Buchfelder; Karl Roessler
Journal:  Wien Klin Wochenschr       Date:  2021-06-15       Impact factor: 1.704

  2 in total

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