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Literature DB >> 21886735

A case of psoriasis worsened by atorvastatin.

Emanuele Cozzani¹, Manuela Scaparro, Aurora Parodi.

Abstract

Statins are known to have a number of cutaneous adverse effects including the induction of autoimmune diseases like systemic and subacute lupus erythematosus, dermatomyositis, polymyositis, lichen planus pemphigoides and the drug reaction with eosinophilia and systemic symptoms (DRESS). Statins have been also reported as a triggering factor of psoriasis. We report a case of psoriasis vulgaris that worsened three months after atorvastatin was introduced and improved after its discontinuance.

Entities: Chemical Disease

Keywords: adverse events; atorvastatin; drug eruptions; psoriasis; statins

Year: 2009 PMID： 21886735 PMCID： PMC3163346 DOI： 10.3315/jdcr.2009.1037

Source DB: PubMed Journal: J Dermatol Case Rep ISSN： 1898-7249

6 in total

Review 1. Lupus erythematosus and other autoimmune diseases related to statin therapy: a systematic review.

Authors: B Noël
Journal: J Eur Acad Dermatol Venereol Date: 2007-01 Impact factor: 6.166

2. [Cutaneous adverse effects of statins].

Authors: J-L Schmutz; A Barbaud; P Tréchot
Journal: Ann Dermatol Venereol Date: 2008-03-04 Impact factor: 0.777

3. [Atorvastatin-induced drug reaction with eosinophilia and systemic symptoms (DRESS)].

Authors: L Gressier; C Pruvost-Balland; L Dubertret; M Viguier
Journal: Ann Dermatol Venereol Date: 2008-11-28 Impact factor: 0.777

4. A mechanistic study on the phototoxicity of atorvastatin: singlet oxygen generation by a phenanthrene-like photoproduct.

Authors: Sara Montanaro; Virginie Lhiaubet-Vallet; MariaRosaria Iesce Iesce; Lucio Previtera; Miguel Angel Miranda
Journal: Chem Res Toxicol Date: 2009-01 Impact factor: 3.739

5. Transition of psoriasiform drug eruption to psoriasis de novo evidenced by histopathology.

Authors: Mayuko Yamamoto; Mitsunori Ikeda; Hajime Kodama; Shigetoshi Sano
Journal: J Dermatol Date: 2008-11 Impact factor: 4.005

Review 6. Drugs in exacerbation of psoriasis.

Authors: E A Abel; L M DiCicco; E K Orenberg; J E Fraki; E M Farber
Journal: J Am Acad Dermatol Date: 1986-11 Impact factor: 11.527

6 in total

4 in total

A case of psoriasis worsened by atorvastatin.

Review 1. Lupus erythematosus and other autoimmune diseases related to statin therapy: a systematic review.

2. [Cutaneous adverse effects of statins].

3. [Atorvastatin-induced drug reaction with eosinophilia and systemic symptoms (DRESS)].

4. A mechanistic study on the phototoxicity of atorvastatin: singlet oxygen generation by a phenanthrene-like photoproduct.

5. Transition of psoriasiform drug eruption to psoriasis de novo evidenced by histopathology.

Review 6. Drugs in exacerbation of psoriasis.

1. Effectiveness of Lipid-Lowering Statin Therapy in Patients With and Without Psoriasis.

2. The effect of statins on psoriasis severity: a meta-analysis of randomized clinical trials.

3. A Case of Psoriasis Vulgaris Aggravated with Atorvastatin, Aided by Concomitant Cyclosporine.

4. Antipsychotic-associated psoriatic rash - a case report.