Uwe Wollina1, Astrid Gemmeke. 1. Department of Dermatology and Allergology, Hospital Dresden-Friedrichstadt, Academic Teaching Hospital of the Technical University of Dresden, 01067 Dresden, Germany.
Abstract
BACKGROUND: Erythema multiforme is a cutaneous reaction that has only rarely been described in varicella zoster virus infection. MAIN OBSERVATIONS: We describe a 76-year old immunocompetent male patient with thoracic herpes zoster. While treated with oral brivudin he developed a widespread cutaneous erythema multiforme. The lesions completely cleared with two weeks with systemic corticosteroids. CONCLUSION: Varicella zoster infections are possible triggers of erythema multiforme and this is the oldest patient reported with such an association. Brivudin itself has not been reported to induce erythema multiforme and is an unlikely cause of disease in our patient.
BACKGROUND:Erythema multiforme is a cutaneous reaction that has only rarely been described in varicella zoster virus infection. MAIN OBSERVATIONS: We describe a 76-year old immunocompetent male patient with thoracic herpes zoster. While treated with oral brivudin he developed a widespread cutaneous erythema multiforme. The lesions completely cleared with two weeks with systemic corticosteroids. CONCLUSION:Varicella zoster infections are possible triggers of erythema multiforme and this is the oldest patient reported with such an association. Brivudin itself has not been reported to induce erythema multiforme and is an unlikely cause of disease in our patient.
Authors: Pietro Quaglino; Marzia Caproni; Emiliano Antiga; Elena Del Bianco; Simona Osella-Abate; Paola Savoia; Alessandra Frezzolini; Donatella Schena; Angelo Marzano; Walter Volpi; Clara De Simone; Aurora Parodi; Paolo Fabbri; Maria Grazia Bernengo Journal: Dermatology Date: 2007 Impact factor: 5.366
Authors: G Gross; H Schöfer; S Wassilew; K Friese; A Timm; R Guthoff; H W Pau; J P Malin; P Wutzler; H W Doerr Journal: J Clin Virol Date: 2003-04 Impact factor: 3.168