BACKGROUND: Angiosarcoma is a malignant tumor of the blood vessels' endothelial lining. The tumor is very aggressive and tends to recur locally and metastasize to distant organs. Commonly, it is associated with different risk factors like lymphoedema, prior radiotherapy but rarely, it may also be associated with chronic venous ulceration. MAIN OBSERVATION: We present a patient with a chronic venous ulceration who developed angiosarcoma of the ulcerated leg with good outcome after treatment. CONCLUSION: It is very important to follow patients with chronic wounds and recognize changes which may be life threatening. In addition to squamous cell carcinoma (Marjolin's tumor), which is most common, angiosarcoma can develop within a venous ulcer.
BACKGROUND:Angiosarcoma is a malignant tumor of the blood vessels' endothelial lining. The tumor is very aggressive and tends to recur locally and metastasize to distant organs. Commonly, it is associated with different risk factors like lymphoedema, prior radiotherapy but rarely, it may also be associated with chronic venous ulceration. MAIN OBSERVATION: We present a patient with a chronic venous ulceration who developed angiosarcoma of the ulcerated leg with good outcome after treatment. CONCLUSION: It is very important to follow patients with chronic wounds and recognize changes which may be life threatening. In addition to squamous cell carcinoma (Marjolin's tumor), which is most common, angiosarcoma can develop within a venous ulcer.
Authors: John A Abraham; Francis J Hornicek; Adam M Kaufman; David C Harmon; Dempsey S Springfield; Kevin A Raskin; Henry J Mankin; David G Kirsch; Andrew E Rosenberg; G Petur Nielsen; Vikram Desphpande; Herman D Suit; Thomas F DeLaney; Sam S Yoon Journal: Ann Surg Oncol Date: 2007-03-14 Impact factor: 5.344
Authors: Jie Xia; DiKe Shi; ZhiWei Wu; Yang Chen; BaoQing Liu; Li Chen; Wongkamchai Metta; YiXiong Zheng Journal: Medicine (Baltimore) Date: 2018-04 Impact factor: 1.889