BACKGROUND: The plexiform schwannoma, a peripheral nerve sheath tumor, is a very rare entity. But dermatologists should be familiar with since they may be the first who make diagnosis possible by taking a deep biopsy. MAIN OBSERVATION: A 24-year-old male presented with multiple asymptomatic subcutaneous nodules of the palmar side of his right hand. Histologic investigations revealed a plexiform schwannoma with numerous Antoni-A areas. There was no evidence of neurofibromatosis type 1 or 2. CONCLUSIONS: Plexiform schwannoma of the hand is a rare nerve sheath tumor. In individual (symptomatic) cases hand surgery is an option that needs a critical indication. In every case histologic investigations are mandatory to confirm the diagnosis and not to overlook the malignant variant of this disease.
BACKGROUND: The plexiform schwannoma, a peripheral nerve sheath tumor, is a very rare entity. But dermatologists should be familiar with since they may be the first who make diagnosis possible by taking a deep biopsy. MAIN OBSERVATION: A 24-year-old male presented with multiple asymptomatic subcutaneous nodules of the palmar side of his right hand. Histologic investigations revealed a plexiform schwannoma with numerous Antoni-A areas. There was no evidence of neurofibromatosis type 1 or 2. CONCLUSIONS: Plexiform schwannoma of the hand is a rare nerve sheath tumor. In individual (symptomatic) cases hand surgery is an option that needs a critical indication. In every case histologic investigations are mandatory to confirm the diagnosis and not to overlook the malignant variant of this disease.
Entities:
Keywords:
nerve sheath tumors; neurofibromatosis; plexiform schwannoma of the hand
Authors: Nicolas Amoretti; Anne Grimaud; Etienne Hovorka; Patrick Chevallier; Christian Roux; Jean Noël Bruneton Journal: Clin Imaging Date: 2006 May-Jun Impact factor: 1.605
Authors: Michal Michal; Dmitry V Kazakov; Irena Belousova; Michele Bisceglia; Michal Zamecnik; Petr Mukensnabl Journal: Virchows Arch Date: 2004-08-20 Impact factor: 4.064