| Literature DB >> 21885279 |
Lee R Roberts1, Duncan Armor, Carolyn Barker, Andrew Bent, Kirstin Bess, Alan Brown, David A Favor, David Ellis, Stephen L Irving, Malcolm MacKenny, Chris Phillips, Nick Pullen, Adam Stennett, Linda Strand, Michelle Styles.
Abstract
A series of p-hydroxybenzenesulphonamides ERβ receptor agonists were discovered and several compounds identified had excellent selectivity over the related ERα receptor. One of these, compound 11, had an interesting binding conformation determined by X-ray and represents an excellent starting point in the quest for further selective ERβ agonists.Entities:
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Year: 2011 PMID： 21885279 DOI： 10.1016/j.bmcl.2011.08.041
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823