Literature DB >> 21884971

HDAC3 at the fulcrum of an epithelial-mesenchymal balance.

Sendurai A Mani1, Michelle Craig Barton.   

Abstract

In this issue of Molecular Cell, Wu et al. (2011) reveal an essential role for a chromatin modifier, histone deacetylase 3 (HDAC3), in hypoxia-induced epithelial-mesenchymal transition (EMT); HIF-activated HDAC3 integrates with WDR5 to impose chromatin modifications that culminate in EMT.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21884971      PMCID： PMC3528183          DOI： 10.1016/j.molcel.2011.08.012

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  10 in total

1.  WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.

Authors:  Joanna Wysocka; Tomek Swigut; Thomas A Milne; Yali Dou; Xin Zhang; Alma L Burlingame; Robert G Roeder; Ali H Brivanlou; C David Allis
Journal:  Cell       Date:  2005-06-17       Impact factor: 41.582

Review 2.  Epithelial-mesenchymal transitions in development and disease.

Authors:  Jean Paul Thiery; Hervé Acloque; Ruby Y J Huang; M Angela Nieto
Journal:  Cell       Date:  2009-11-25       Impact factor: 41.582

3.  Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition.

Authors:  Min-Zu Wu; Ya-Ping Tsai; Muh-Hwa Yang; Chi-Hung Huang; Shyue-Yih Chang; Cheng-Chi Chang; Shu-Chun Teng; Kou-Juey Wu
Journal:  Mol Cell       Date:  2011-09-02       Impact factor: 17.970

4.  HDAC3 is a critical negative regulator of long-term memory formation.

Authors:  Susan C McQuown; Ruth M Barrett; Dina P Matheos; Rebecca J Post; George A Rogge; Theresa Alenghat; Shannon E Mullican; Steven Jones; James R Rusche; Mitchell A Lazar; Marcelo A Wood
Journal:  J Neurosci       Date:  2011-01-12       Impact factor: 6.167

5.  Direct regulation of TWIST by HIF-1alpha promotes metastasis.

Authors:  Muh-Hwa Yang; Min-Zu Wu; Shih-Hwa Chiou; Po-Min Chen; Shyue-Yih Chang; Chung-Ji Liu; Shu-Chun Teng; Kou-Juey Wu
Journal:  Nat Cell Biol       Date:  2008-02-24       Impact factor: 28.824

Review 6.  Epithelial-mesenchymal transition and its implications for fibrosis.

Authors:  Raghu Kalluri; Eric G Neilson
Journal:  J Clin Invest       Date:  2003-12       Impact factor: 14.808

7.  Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control.

Authors:  Srividya Bhaskara; Brenda J Chyla; Joseph M Amann; Sarah K Knutson; David Cortez; Zu-Wen Sun; Scott W Hiebert
Journal:  Mol Cell       Date:  2008-04-11       Impact factor: 17.970

8.  The epithelial-mesenchymal transition generates cells with properties of stem cells.

Authors:  Sendurai A Mani; Wenjun Guo; Mai-Jing Liao; Elinor Ng Eaton; Ayyakkannu Ayyanan; Alicia Y Zhou; Mary Brooks; Ferenc Reinhard; Cheng Cheng Zhang; Michail Shipitsin; Lauren L Campbell; Kornelia Polyak; Cathrin Brisken; Jing Yang; Robert A Weinberg
Journal:  Cell       Date:  2008-05-16       Impact factor: 41.582

9.  Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

Authors:  Bryan T Hennessy; Ana-Maria Gonzalez-Angulo; Katherine Stemke-Hale; Michael Z Gilcrease; Savitri Krishnamurthy; Ju-Seog Lee; Jane Fridlyand; Aysegul Sahin; Roshan Agarwal; Corwin Joy; Wenbin Liu; David Stivers; Keith Baggerly; Mark Carey; Ana Lluch; Carlos Monteagudo; Xiaping He; Victor Weigman; Cheng Fan; Juan Palazzo; Gabriel N Hortobagyi; Laura K Nolden; Nicholas J Wang; Vicente Valero; Joe W Gray; Charles M Perou; Gordon B Mills
Journal:  Cancer Res       Date:  2009-05-12       Impact factor: 12.701

Review 10.  The many roles of histone deacetylases in development and physiology: implications for disease and therapy.

Authors:  Michael Haberland; Rusty L Montgomery; Eric N Olson
Journal:  Nat Rev Genet       Date:  2009-01       Impact factor: 53.242
  10 in total
  2 in total

1.  Targeting histone deacetylase-3 blocked epithelial-mesenchymal plasticity and metastatic dissemination in gastric cancer.

Authors:  Sheng-Mao Wu; Yee-Jee Jan; Shih-Chuan Tsai; Hung-Chuan Pan; Chin-Chang Shen; Cheng-Ning Yang; Shu-Hua Lee; Shing-Hwa Liu; Li-Wei Shen; Chien-Shan Chiu; Jack L Arbiser; Menghsiao Meng; Meei-Ling Sheu
Journal:  Cell Biol Toxicol       Date:  2022-01-01       Impact factor: 6.691

2.  PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407.

Authors:  Xin Tan; Shuai Chen; Jiangxue Wu; Jiaxin Lin; Changchuan Pan; Xiaofang Ying; Zhizhong Pan; Lin Qiu; Ranyi Liu; Rong Geng; Wenlin Huang
Journal:  Cell Death Dis       Date:  2017-03-16       Impact factor: 8.469
  2 in total

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