OBJECTIVE: To evaluate whether DW-MRI improves the detection of pelvic lymph nodes metastates in patients with bladder cancer undergoing radical cystectomy. PATIENTS AND METHODS: 36 patients with CT scan negative for nodal metastates underwent DW-MRI before surgery. Diagnostic accuracy of DW-MRI was compared with histopathological findings. RESULTS: Mean ADC value was 0.85 × 10(-3) mm(3)/s in the nodal metastatic group and 1 × 10(-3) mm(3)/s in the nodal non-metastatic group (P = 0.02). The ADC cut-off value, obtained by the ROC curve was 0.86 × 10(-3) mm(3)/s. Patient-based sensitivity, specificity and positive and negative predictive values were 76.4%, 89.4%, 26.6%, and 71.4%, respectively. CONCLUSION: DW-MRI may be used to differentiate metastatic from non-metastatic lymph nodes in patients with high-grade bladder cancer.
OBJECTIVE: To evaluate whether DW-MRI improves the detection of pelvic lymph nodes metastates in patients with bladder cancer undergoing radical cystectomy. PATIENTS AND METHODS: 36 patients with CT scan negative for nodal metastates underwent DW-MRI before surgery. Diagnostic accuracy of DW-MRI was compared with histopathological findings. RESULTS: Mean ADC value was 0.85 × 10(-3) mm(3)/s in the nodal metastatic group and 1 × 10(-3) mm(3)/s in the nodal non-metastatic group (P = 0.02). The ADC cut-off value, obtained by the ROC curve was 0.86 × 10(-3) mm(3)/s. Patient-based sensitivity, specificity and positive and negative predictive values were 76.4%, 89.4%, 26.6%, and 71.4%, respectively. CONCLUSION: DW-MRI may be used to differentiate metastatic from non-metastatic lymph nodes in patients with high-grade bladder cancer.
Authors: William P Parker; Philip L Ho; Stephen A Boorjian; Jonathan J Melquist; Prabin Thapa; Jeffrey M Holzbeierlein; Igor Frank; Ashish M Kamat; Eugene K Lee Journal: World J Urol Date: 2016-03-04 Impact factor: 4.226
Authors: Harriet C Thoeny; Sebastiano Barbieri; Johannes M Froehlich; Baris Turkbey; Peter L Choyke Journal: Radiology Date: 2017-12 Impact factor: 11.105
Authors: Sebastian Christoph Schmid; Tina Zahel; Bernhard Haller; Thomas Horn; Ilja Metzger; Konstantin Holzapfel; Anna K Seitz; Jürgen Erich Gschwend; Margitta Retz; Tobias Maurer Journal: World J Urol Date: 2015-08-11 Impact factor: 4.226