Literature DB >> 21883039

Antiproliferative activity of some 1,4-dimethylcarbazoles on cells that express estrogen receptors: part I.

Anna Caruso1, Adele Chimento, Hussein El-Kashef, Jean-Charles Lancelot, Antonella Panno, Vincenzo Pezzi, Carmela Saturnino, Maria Stefania Sinicropi, Rosa Sirianni, Sylvain Rault.   

Abstract

Several 9H-carbazole derivatives are used for various pharmacological applications. Many of these compounds demonstrated cytotoxic and anticancer activities. In this work, we have investigated the cytotoxic activity of some substituted carbazoles against cancer cell lines (MCF-7, and ISK). The derivative 2a showed the highest inhibitory activity against both cell lines.

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Year:  2011        PMID： 21883039     DOI： 10.3109/14756366.2011.603132

Source DB:  PubMed          Journal:  J Enzyme Inhib Med Chem        ISSN： 1475-6366            Impact factor:   5.051


  4 in total

1.  Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents.

Authors:  Cornelis P Vlaar; Linette Castillo-Pichardo; Julia I Medina; Cathyria M Marrero-Serra; Ericka Vélez; Zulma Ramos; Eliud Hernández
Journal:  Bioorg Med Chem       Date:  2018-01-11       Impact factor: 3.641

2.  Acetylated hyaluronic acid: enhanced bioavailability and biological studies.

Authors:  Carmela Saturnino; Maria Stefania Sinicropi; Ortensia Ilaria Parisi; Domenico Iacopetta; Ada Popolo; Stefania Marzocco; Giuseppina Autore; Anna Caruso; Anna Rita Cappello; Pasquale Longo; Francesco Puoci
Journal:  Biomed Res Int       Date:  2014-07-08       Impact factor: 3.411

Review 3.  Tumour biomarkers: homeostasis as a novel prognostic indicator.

Authors:  Michela Falco; Giuseppe Palma; Domenica Rea; Davide De Biase; Stefania Scala; Massimiliano D'Aiuto; Gaetano Facchini; Sisto Perdonà; Antonio Barbieri; Claudio Arra
Journal:  Open Biol       Date:  2016-12       Impact factor: 6.411

4.  N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation.

Authors:  Maria Stefania Sinicropi; Domenico Iacopetta; Camillo Rosano; Rosario Randino; Anna Caruso; Carmela Saturnino; Noemi Muià; Jessica Ceramella; Francesco Puoci; Manuela Rodriquez; Pasquale Longo; Maria Rosaria Plutino
Journal:  J Enzyme Inhib Med Chem       Date:  2018-12       Impact factor: 5.051
  4 in total

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