Literature DB >> 21882199

Is a level III dissection necessary for a positive sentinel lymph node in melanoma?

Jukes P Namm1, Alfred E Chang, Vincent M Cimmino, Riley S Rees, Timothy M Johnson, Michael S Sabel.   

Abstract

BACKGROUND: For melanoma patients with a positive axillary SLN, the extent of ALND remains controversial, with debate over whether a level III dissection is needed.
METHODS: We queried our IRB approved prospective database for patients with a positive axillary SLN who had a level I/II dissection only, and compared recurrence and complication rates to the existing literature.
RESULTS: Between 1998 and 2008, 270 patients had 285 level I/II ALNDs for a positive SLN. Median number of SLN removed was 2, while the median number of involved SLN was 1 (range 1-4). An average of 18.7 nodes/ALND were removed, with 13% having positive non-SLN. Post-operative complications occurred in 31 patients (11%), primarily cellulitis (8%). After a mean follow-up of 44 months, 14 patients had a regional recurrence in the axillary basin (5%).
CONCLUSIONS: The complication rate and regional recurrence rate for patients undergoing a level I/II ALND for a positive SLN are either lower than or on par with reported series of ALND for level I, II, and III dissections, suggesting that in this setting, the level III dissection may be of minimal benefit.
Copyright © 2011 Wiley Periodicals, Inc.

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Year:  2011        PMID: 21882199     DOI: 10.1002/jso.22076

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  3 in total

1.  Frequency of level II and III axillary nodes metastases in patients with positive sentinel lymph nodes in melanoma: a multi-institutional study in Japan.

Authors:  Arata Tsutsumida; Akira Takahashi; Kenjiro Namikawa; Naoya Yamazaki; Hisashi Uhara; Yukiko Teramoto; Tatsuya Takenouchi; Satoshi Fukushima; Kenji Yokota; Jiro Uehara; Shigeto Matsushita; Yoshitsugu Shibayama; Naohito Hatta; Yuri Masui; Hiroshi Uchi; Yasuhiro Fujisawa; Dai Ogata
Journal:  Int J Clin Oncol       Date:  2016-01-13       Impact factor: 3.402

2.  Dominant lymph drainage in the upper extremity and upper trunk region: evaluation of lymph drainage in patients with skin melanomas.

Authors:  Toshihiko Hayashi; Hiroshi Furukawa; Akihiko Oyama; Emi Funayama; Akira Saito; Yuhei Yamamoto
Journal:  Int J Clin Oncol       Date:  2012-12-08       Impact factor: 3.402

3.  Recent Evolution in the Management of Lymph Node Metastases in Melanoma.

Authors:  Shelby Breit; Elise Foley; Elizabeth Ablah; Hayrettin Okut; Joshua Mammen
Journal:  Kans J Med       Date:  2021-03-19
  3 in total

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