Literature DB >> 21881711

Thrombocytopenia in cardiac surgery: diagnostic and prognostic importance.

Ederlon Rezende1, Gustavo Morais, João Manoel Silva Junior, Amanda Maria Ribas Rosa de Oliveira, Jose Marconi Almeida Souza, Diogo Oliveira Toledo, Ivo Richter, Enock Meira Brandão.   

Abstract

OBJECTIVE: Patients undergo to cardiac surgery have more probability to develop thrombocytopenia. The heparin induced thrombocytopenia happens in 5% of the patients. The aim from this study was to evaluate the clinical importance from the severe thrombocytopenia in postoperative cardiac surgical patients.
METHODS: It was included cardiac surgical patients with platelets < 150000 cel/mm³ during firsts 24 h from postoperative. All patients underwent evaluation for four Ts score (thrombocytopenia, use preview of heparin, thrombosis and platelets decreased not related to heparin). In order to a four Ts score e" 6 was considered as suggestive of heparin induced thrombocytopenia type II. The mortality rate in intensive care (ICU) and hospital, length of stay, healthy state and incidence from thrombosis were compared in patients with score > 6 (group 1) and < 6 (group 2).
RESULTS: It was include 120 patients who met the inclusions criterions. There was no difference between the groups in related to age, gender, time of cardiopulmonary bypass and surgery. However, the incidence of thrombosis was higher in group 1 (23% vs. 0%, P<0.0001), as well as the greater score is related to higher hospital mortality rate.
CONCLUSION: The score > 6, in postoperative cardiac surgical patients, it is associated to higher incidence of thrombosis as well as the greater score is related to higher hospital mortality rate.

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Year:  2011        PMID: 21881711     DOI: 10.1590/s0102-76382011000100011

Source DB:  PubMed          Journal:  Rev Bras Cir Cardiovasc


  3 in total

1.  A principal component analysis of postinjury viscoelastic assays: clotting factor depletion versus fibrinolysis.

Authors:  Theresa L Chin; Ernest E Moore; Hunter B Moore; Eduardo Gonzalez; Michael P Chapman; John R Stringham; Christopher R Ramos; Anirban Banerjee; Angela Sauaia
Journal:  Surgery       Date:  2014-06-21       Impact factor: 3.982

2.  A case of thrombocytopenia associated with the use of hydroxychloroquine following open heart surgery.

Authors:  Deniz Demir; Fatih Öcal; Mustafa Abanoz; Hasan Dermenci
Journal:  Int J Surg Case Rep       Date:  2014-11-20

3.  Thrombocytopenia After Transcatheter Valve-in-Valve Implantation: Prognostic Marker or Mere Finding?

Authors:  Renato C de Souza; Leonardo Paim; Guilherme Viotto; Joaquim Aprigio; Lucas L Araújo; Henrique Ribeiro; Roney O Sampaio; Flavio Tarasoutchi; Pablo M A Pomerantzeff; José Honório Palma; Fabio B Jatene
Journal:  Braz J Cardiovasc Surg       Date:  2018 Jul-Aug
  3 in total

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