Literature DB >> 2187907

Immunohistochemical detection of neuroblastoma in frozen sections of bone marrow trephine biopsy specimens.

M M Reid1, A J Malcolm, A G McGuckin.   

Abstract

Frozen sections from bone marrow trephine biopsy specimens from children with disseminated neuroblastoma were stained using the monoclonal antibody UJ13A. An immunoalkaline phosphatase technique was the preferred staining method. Acceptable histological detail was obtained from this material and deposits of tumour cells detected. Some apparently fibrous tissue was also stained by this antibody. The results show that this immunohistological approach is feasible and provide encouragement for its addition to the range of investigations currently available for assessing the marrows of children with this disease.

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Year:  1990        PMID： 2187907      PMCID： PMC502377          DOI： 10.1136/jcp.43.4.334

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  5 in total

1.  Histology of neuroblastoma involving bone marrow.

Authors:  J W Ironside; C R Shiach; A C Cuthbert; E A Robinson
Journal:  Br J Haematol       Date:  1989-04       Impact factor: 6.998

2.  Bone marrow examination in neuroblastoma patients: a morphologic, immunocytochemical, and immunohistochemical study.

Authors:  B R Oppedal; I Storm-Mathisen; J T Kemshead; P Brandtzaeg
Journal:  Hum Pathol       Date:  1989-08       Impact factor: 3.466

3.  Immunocytochemical detection of tumours of neuroectodermal origin.

Authors:  P J Carey; A J Malcolm; A D Pearson; J T Kemshead; M M Reid
Journal:  J Clin Pathol       Date:  1988-05       Impact factor: 3.411

4.  Histology of neuroblastoma involving bone marrow: the problem of detecting residual tumour after initiation of chemotherapy.

Authors:  M M Reid; P J Hamilton
Journal:  Br J Haematol       Date:  1988-08       Impact factor: 6.998

5.  Immunocytochemical examination of bone marrow in disseminated neuroblastoma.

Authors:  P J Carey; L Thomas; G Buckle; M M Reid
Journal:  J Clin Pathol       Date:  1990-01       Impact factor: 3.411
  5 in total
  1 in total

1.  Routine histological compared with immunohistological examination of bone marrow trephine biopsy specimens in disseminated neuroblastoma.

Authors:  M M Reid; J P Wallis; A G McGuckin; A D Pearson; A J Malcolm
Journal:  J Clin Pathol       Date:  1991-06       Impact factor: 3.411
  1 in total

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