Literature DB >> 21878658

Drug-related problems detected in Australian Community Pharmacies: The PROMISe Trial.

Mackenzie Williams1, Gregory M Peterson, Peter C Tenni, Ivan K Bindoff, Colin Curtain, Josephine Hughes, Luke Re Bereznicki, Shane L Jackson, David Cm Kong, Jeff D Hughes.   

Abstract

BACKGROUND: Drug-related problems (DRPs) are a major burden on health care systems. Community pharmacists are ideally placed to detect, prevent, and resolve these DRPs.
OBJECTIVE: To determine the number and nature of DRPs detected and clinical interventions performed by Australian community pharmacists, using an electronic system.
METHODS: An electronic documentation system was designed and integrated into the existing dispensing software of 186 pharmacies to allow pharmacists to record details about the clinical interventions they performed to prevent or resolve DRPs. Participating pharmacies were randomly allocated to 3 groups: group 1 had documentation software, group 2 had documentation software plus a timed reminder to document interventions, and group 3 had documentation software, a timed reminder, and an electronic decision support prompt. Pharmacists classified DRPs, entered recommendations they made, and estimated the clinical significance of the intervention. An observational substudy that included pharmacies without any documentation software was completed to verify intervention rates.
RESULTS: Over 12 weeks, 531 participating pharmacists recorded 6230 clinical interventions from 2,013,923 prescriptions, with a median intervention rate of 0.23% of prescriptions. No significant differences were seen between the 3 groups that used documentation software; as expected, however, the pharmacies that used this software had a significantly higher documentation rate compared to the pharmacies without documentation software. The most common interventions were related to drug selection problems (30.8%) and educational issues (24.4%). Recommendations were often related to a change in therapy (40.0%), and 41.6% of interventions were self-rated as highly significant. Drug groups most commonly subject to an intervention included antibiotics, glucocorticoids, nonsteroidal antiinflammatory drugs, and opioids.
CONCLUSIONS: The documentation system allowed for the determination of the frequency and types of DRPs, as well as the recommendations made to resolve them in community pharmacy practice. Use of the software, including its electronic prompts, significantly increased the documentation of interventions by pharmacists.

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Year:  2011        PMID: 21878658     DOI: 10.1345/aph.1Q138

Source DB:  PubMed          Journal:  Ann Pharmacother        ISSN: 1060-0280            Impact factor:   3.154


  14 in total

Review 1.  Tools for Assessing Potential Significance of Pharmacist Interventions: A Systematic Review.

Authors:  Thi-Ha Vo; Bruno Charpiat; Claire Catoire; Michel Juste; Renaud Roubille; François-Xavier Rose; Sébastien Chanoine; Jean-Luc Bosson; Ornella Conort; Benoît Allenet; Pierrick Bedouch
Journal:  Drug Saf       Date:  2016-02       Impact factor: 5.606

2.  Expanded prescribing: a comparison of the views of Australian hospital and community pharmacists.

Authors:  Kreshnik Hoti; Jeffery Hughes; Bruce Sunderland
Journal:  Int J Clin Pharm       Date:  2013-04-03

Review 3.  Application of drug-related problem (DRP) classification systems: a review of the literature.

Authors:  Benjamin J Basger; Rebekah J Moles; Timothy F Chen
Journal:  Eur J Clin Pharmacol       Date:  2014-05-02       Impact factor: 2.953

4.  A web-based training program to support chronic kidney disease screening by community pharmacists.

Authors:  Pankti A Gheewala; Gregory M Peterson; Syed Tabish R Zaidi; Luke Bereznicki; Matthew D Jose; Ronald L Castelino
Journal:  Int J Clin Pharm       Date:  2016-06-21

Review 5.  The effects of on-screen, point of care computer reminders on processes and outcomes of care.

Authors:  Kaveh G Shojania; Alison Jennings; Alain Mayhew; Craig R Ramsay; Martin P Eccles; Jeremy Grimshaw
Journal:  Cochrane Database Syst Rev       Date:  2009-07-08

6.  A retrospective analysis of drug-related problems documented in a national database.

Authors:  Tommy Westerlund; Ulrika Gelin; Elisabeth Pettersson; Fredrik Skärlund; Kajsa Wågström; Carina Ringbom
Journal:  Int J Clin Pharm       Date:  2012-11-28

7.  An exploration of clinical interventions provided by pharmacists within a complex asthma service.

Authors:  Kate S Lemay; Bandana Saini; Sinthia Bosnic-Anticevich; Lorraine Smith; Kay Stewart; Lynne Emmerton; Deborah L Burton; Ines Krass; Carol L Armour
Journal:  Pharm Pract (Granada)       Date:  2015-03-15

8.  The difference in pharmacists' interventions across the diverse settings in a children's hospital.

Authors:  Hesty Utami Ramadaniati; Ya Ping Lee; Jeffery David Hughes
Journal:  PLoS One       Date:  2014-10-08       Impact factor: 3.240

9.  Majority of drug-related problems identified during medication review are not associated with STOPP/START criteria.

Authors:  Sanne Verdoorn; Henk-Frans Kwint; Adrianne Faber; Jacobijn Gussekloo; Marcel L Bouvy
Journal:  Eur J Clin Pharmacol       Date:  2015-08-07       Impact factor: 2.953

Review 10.  Mapping the terrain: A conceptual schema for a mental health medication support service in community pharmacy.

Authors:  Shane Scahill; Jane L Fowler; H Laetitia Hattingh; Fiona Kelly; Amanda J Wheeler
Journal:  SAGE Open Med       Date:  2015-09-30
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