| Literature DB >> 21877232 |
Mário Rodrigues de Melo Filho1, Célsia Adriane Dias da Silva, Maurício da Rocha Dourado, Maria Betânia de Oliveira Pires, Sabina Pena Borges Pêgo, Edmilson Martins de Freitas.
Abstract
The side-effects of many drugs manifest in the oral mucosa. The anti-malarial agent chloroquine diphosphate, which is also used to treat immunological, dermatological, and rheumatological disorders, usually causes pigmentary changes in the oral mucosa. This report presents a case of palate pigmentation related to the prolonged use of chloroquine diphosphate caused by the deposition of drug metabolites in the mucosa. Healthcare professionals must be aware of these drugs and their adverse effects in order to make the correct diagnosis, decide on the optimal treatment for the condition, or refer the patient to an appropriate specialist.Entities:
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Year: 2011 PMID： 21877232 PMCID： PMC3311937 DOI： 10.1007/s12105-011-0288-5
Source DB: PubMed Journal: Head Neck Pathol ISSN： 1936-055X