OBJECTIVE: The relationship between brain tumors and cognitive deficits is well established in the literature. However, studies investigating the cognitive status in low and high-grade gliomas patients are scarce, particularly in patients with average or lower educational level. This study aimed at investigating the cognitive functioning in a sample of patients with low and high-grade gliomas before surgical intervention. METHOD: The low-grade (G1, n=19) and high-grade glioma (G2, n=8) patients underwent a detailed neuropsychological assessment of memory, executive functions, visuo-perceptive and visuo-spatial abilities, intellectual level and language. RESULTS: There was a significant impairment on verbal and visual episodic memory, executive functions including mental flexibility, nominal and categorical verbal fluency and speed of information processing in G2. G1 showed only specific deficits on verbal and visual memory recall, mental flexibility and processing speed. CONCLUSION: These findings demonstrated different levels of impairments in the executive and memory domains in patients with low and high grade gliomas.
OBJECTIVE: The relationship between brain tumors and cognitive deficits is well established in the literature. However, studies investigating the cognitive status in low and high-grade gliomaspatients are scarce, particularly in patients with average or lower educational level. This study aimed at investigating the cognitive functioning in a sample of patients with low and high-grade gliomas before surgical intervention. METHOD: The low-grade (G1, n=19) and high-grade glioma (G2, n=8) patients underwent a detailed neuropsychological assessment of memory, executive functions, visuo-perceptive and visuo-spatial abilities, intellectual level and language. RESULTS: There was a significant impairment on verbal and visual episodic memory, executive functions including mental flexibility, nominal and categorical verbal fluency and speed of information processing in G2. G1 showed only specific deficits on verbal and visual memory recall, mental flexibility and processing speed. CONCLUSION: These findings demonstrated different levels of impairments in the executive and memory domains in patients with low and high grade gliomas.
Authors: Christina Weyer-Jamora; Melissa S Brie; Tracy L Luks; Ellen M Smith; Steve E Braunstein; Javier E Villanueva-Meyer; Paige M Bracci; Susan Chang; Shawn L Hervey-Jumper; Jennie W Taylor Journal: Neurooncol Pract Date: 2020-11-04
Authors: Christina Weyer-Jamora; Melissa S Brie; Tracy L Luks; Ellen M Smith; Shawn L Hervey-Jumper; Jennie W Taylor Journal: Neurosurgery Date: 2021-11-18 Impact factor: 5.315
Authors: Eliane C Miotto; Joana B Balardin; Gilson Vieira; Joao R Sato; Maria da Graça M Martin; Milberto Scaff; Manoel J Teixeira; Edson Amaro Junior Journal: PLoS One Date: 2014-08-26 Impact factor: 3.240
Authors: Emma van Kessel; Anniek E Baumfalk; Martine J E van Zandvoort; Pierre A Robe; Tom J Snijders Journal: J Neurooncol Date: 2017-05-31 Impact factor: 4.130
Authors: Djaina Satoer; Elke De Witte; Marion Smits; Roelien Bastiaanse; Arnaud Vincent; Peter Mariën; Evy Visch-Brink Journal: Case Rep Neurol Med Date: 2017-06-22