Literature DB >> 21876920

[Influence of maternal and neonatal factors on bronchopulmonary dysplasia development].

Marcela Raquel de Oliveira Lima1, Maria do Amparo Andrade, Ana Paula Guimarães de Araújo, José Natal Figueroa, Lívia Barboza de Andrade.   

Abstract

OBJECTIVE: To review epidemiological features of bronchopulmonary dysplasia (BPD) and its relationship with maternal and neonatal conditions in a neonatal unit.
METHODS: Cross-sectional, descriptive and analytical study involving preterm newborns (NBs) with a birth weight lower than 1,500 g and gestational age under 37 weeks. Data was collected through a review of medical records of these newborns admitted to a neonatal unit.
RESULTS: The study included 323 newborns with a mean birth weight of 1,161 g (± 231 g), gestational age between 24 and 36.5 weeks, with a BPD incidence of 17.6%. Among the NBs developing BPD, the mean of days using invasive mechanical ventilation (IMV), non-invasive ventilation (NIMV), and supplemental oxygen was 17.6, 16.2, and 46.1 days, respectively, with a time significantly longer for those NBs developing BPD (p < 0.001). BPD occurred significantly more often in NBs with a patent ductus arteriosus (PDA).
CONCLUSION: BPD incidence in this study was similar to that found in the literature. No BPD association with maternal infection and antenatal corticosteroid use was found. NBs receiving exogenous surfactant had a higher BPD incidence because they had lower BW and GA. Concomitant occurrence of PDA and BPD is associated with staying longer on IMV, NIMV and supplemental oxygen.

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Year:  2011        PMID: 21876920     DOI: 10.1590/s0104-42302011000400012

Source DB:  PubMed          Journal:  Rev Assoc Med Bras (1992)        ISSN: 0104-4230            Impact factor:   1.209


  2 in total

Review 1.  Efficacy and safety of surfactant replacement therapy for preterm neonates with respiratory distress syndrome in low- and middle-income countries: a systematic review.

Authors:  M J Sankar; N Gupta; K Jain; R Agarwal; V K Paul
Journal:  J Perinatol       Date:  2016-05       Impact factor: 2.521

2.  Assessment of the neuropsychomotor development in the first year of life of premature infants with and without bronchopulmonary dysplasia.

Authors:  Letycia Vieira Silva; Lúcio Borges de Araújo; Vivian Mara Gonçalves de Oliveira Azevedo
Journal:  Rev Bras Ter Intensiva       Date:  2018 Apr-Jun
  2 in total

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