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Literature DB >> 21876778

Coronary spasm-related acute myocardial infarction in a patient with essential thrombocythemia.

Abstract

We report a case of essential thrombocythemia (ET) in a 30-year-old female who exhibited inferior wall ST-elevation acute myocardial infarction (AMI) without significant obstructive coronary artery disease. Right coronary vasospasm was observed after intra-coronary methylergonovine administration and she received verapamil 120 mg/dthereafter and hydroxyurea 1500 mg/d for thrombocythemia. After discontinuation of the hydroxyurea for 9 mo based on the impression of coronary spasm-related instead of coronary thrombosis-related AMI, her platelet count rose but no chest pain was observed. It is suggested that coronary spasm potentially plays a role in patients with ET, AMI and no significant coronary artery stenosis.

Entities: Chemical Disease Species

Keywords: Acute myocardial infarction; Coronary spasm; Essential thrombocythemia

Year: 2011 PMID： 21876778 PMCID： PMC3163243 DOI： 10.4330/wjc.v3.i8.278

Source DB: PubMed Journal: World J Cardiol

10 in total

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Authors: Alexandra P Wolanskyj; Susan M Schwager; Rebecca F McClure; Dirk R Larson; Ayalew Tefferi
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