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Literature DB >> 21875658

Physiopathology of the cochlear microcirculation.

Abstract

Normal blood supply to the cochlea is critically important for establishing the endocochlear potential and sustaining production of endolymph. Abnormal cochlear microcirculation has long been considered an etiologic factor in noise-induced hearing loss, age-related hearing loss (presbycusis), sudden hearing loss or vestibular function, and Meniere's disease. Knowledge of the mechanisms underlying the pathophysiology of cochlear microcirculation is of fundamental clinical importance. A better understanding of cochlear blood flow (CoBF) will enable more effective management of hearing disorders resulting from aberrant blood flow. This review focuses on recent discoveries and findings related to the physiopathology of the cochlear microvasculature. Published by Elsevier B.V.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2011 PMID： 21875658 PMCID： PMC3608480 DOI： 10.1016/j.heares.2011.08.006

Source DB: PubMed Journal: Hear Res ISSN： 0378-5955 Impact factor: 3.208

207 in total

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Journal: Hear Res Date: 1997-03 Impact factor: 3.208

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Journal: J Physiol Date: 1994-11-01 Impact factor: 5.182

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Authors: D D Gruber; H Dang; M Shimozono; M A Scofield; P Wangemann
Journal: Hear Res Date: 1998-05 Impact factor: 3.208

10. Pharmacological reversal of endothelin-1 mediated constriction of the spiral modiolar artery: a potential new treatment for sudden sensorineural hearing loss.

Authors: Elias Q Scherer; Wolfgang Arnold; Philine Wangemann
Journal: BMC Ear Nose Throat Disord Date: 2005-11-29

53 in total

1. Non-invasive intraoperative monitoring of cochlear function by cochlear microphonics during cerebellopontine-angle surgery.

Authors: Blandine Lourenço; Béatriz Madero; Stéphane Tringali; Xavier Dubernard; Toufic Khalil; André Chays; Arnaud Bazin; Thierry Mom; Paul Avan
Journal: Eur Arch Otorhinolaryngol Date: 2017-10-27 Impact factor: 2.503

2. Cadmium, obesity, and education, and the 10-year incidence of hearing impairment: The beaver dam offspring study.

Authors: Dayna S Dalton; Carla R Schubert; Alex Pinto; Mary E Fischer; Guan-Hua Huang; Barbara E K Klein; Ronald Klein; James S Pankow; Adam J Paulsen; Michael Y Tsai; Ted S Tweed; Karen J Cruickshanks
Journal: Laryngoscope Date: 2019-08-19 Impact factor: 3.325

Physiopathology of the cochlear microcirculation.

Review 1. Endothelial-pericyte interactions in angiogenesis.

Review 2. Role of pericytes in vascular morphogenesis.

Review 3. Microvascular pericytes: a review of their morphological and functional characteristics.

4. Student Research Award 1990. Catecholaminergic innervation of the inner ear.

5. Increased laminin deposition in capillaries of the stria vascularis of quiet-aged gerbils.

Review 6. Electrically stimulated increases in cochlear blood flow: I. Frequency and intensity effects.

7. Cochlear blood flow in endolymphatic hydrops.

8. Neuronal regulation of cochlear blood flow in the guinea-pig.

9. Alpha1A-adrenergic receptors mediate vasoconstriction of the isolated spiral modiolar artery in vitro.

10. Pharmacological reversal of endothelin-1 mediated constriction of the spiral modiolar artery: a potential new treatment for sudden sensorineural hearing loss.

1. Non-invasive intraoperative monitoring of cochlear function by cochlear microphonics during cerebellopontine-angle surgery.

2. Cadmium, obesity, and education, and the 10-year incidence of hearing impairment: The beaver dam offspring study.

3. Progression of Hearing Loss in the Aging Population: Repeated Auditory Measurements in the Rotterdam Study.

4. Is drug consumption correlated with benign paroxysmal positional vertigo (BPPV) recurrence?

5. Slc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction.

6. Vascular Pathophysiology in Hearing Disorders.

7. Structural changes in thestrial blood-labyrinth barrier of aged C57BL/6 mice.

8. Prospective Study of Dietary Patterns and Hearing Threshold Elevation.

Review 9. Auditory function and dysfunction: estrogen makes a difference.

10. Hyaluronan up-regulation is linked to renal dysfunction and hearing loss induced by silver nanoparticles.