| Literature DB >> 21875065 |
Feng Zhang1, Saheem Zaidi, Kendra M Haney, Glen E Kellogg, Yan Zhang.
Abstract
The syntheses of the natural product anibamine and its three olefin isomers have been achieved concisely and efficiently via highly regio- and stereoselective reactions. The crucial steps included a regioselective palladium-catalyzed alkynylation by Sonogashira coupling and a stereoselective Suzuki coupling. Further conformation analyses and in vitro calcium mobilization studies were carried out to characterize the compounds' biological properties.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21875065 PMCID： PMC3197777 DOI： 10.1021/jo2013669
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354